dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000346
Uniprot Accession O08739; AMPD3_MOUSE; O88692; Q8CFR4;
Genbank Protein ID NP_001263230.1; NP_033797.2; XP_006507285.1;
Genbank Nucleotide ID NM_001276301.1; NM_009667.3; XM_006507222.2;
Protein Name AMP deaminase 3
Protein Synonyms/Alias AMP deaminase H-type;AMP deaminase isoform E;Heart-type AMPD;
Gene Name Ampd3
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)		 AMP deaminase plays a critical role in energy metabolism.
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
77ETAKRKKSFKMIRSQPhosphoSitePlus22135298
83KSFKMIRSQSLSLQMdbPTM 3.0;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;curated18846507; 19367708; 20139300; 21183079; 21659605; 16381945;
85FKMIRSQSLSLQMPTdbPTM 3.0;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;curated19367708; 20139300; 21183079; 16381945; 23193290; 21081558;
87MIRSQSLSLQMPTQQPhosphoSitePlus22135298
101QDWKGPPTASPAMSPcurated25338131
103WKGPPTASPAMSPATcurated25338131
107PTASPAMSPATPLVPPhosphoSitePlus;curated22135298; 25338131
532VDDESKHSDHMFSDKPhosphoSitePlus22135298
537KHSDHMFSDKSPSPDPhosphoSitePlus22135298
Sequence
(Fasta)		MPRQFPKLNM SDLDEHVRLL AEKVFAKVLR EEDSKDVMSL FTVPEDCPIG QKEAKERELQ 60
KELAEQKSVE TAKRKKSFKM IRSQSLSLQM PTQQDWKGPP TASPAMSPAT PLVPGATSKP 120
GPAPYAMPEY QRVTISGDYC AGITVEDYEQ AAKSLAKALM IREKYARLAY HRFPRTTAQY 180
LAHQGESVPL EEGLPDFHPP PLPQEDPYCL DDAPPNLGYL VRMHGGVLFV YDNQTMLERQ 240
EPHSLPYPDL ETYIVDMSHI LALITDGPTK TYCHRRLNFL ESKFSLHEML NEMSEFKELK 300
SNPHRDFYNV RKVDTHIHAA ACMNQKHLLR FIKHTYQTEP DRTVAEKLGR KITLRQVFDS 360
LHMDPYDLTV DSLDVHAGRQ TFHRFDKFNS KYNPVGASEL RDLYLKTENY LGGEYFARMV 420
KEVARELEDS KYQYSEPRLS IYGRSPKEWS SLARWFIQHK VYSPNMRWII QVPRIYDIFR 480
SKKLLPNFGK MLENIFLPLF KATINPQDHR ELHLFLKYVT GFDSVDDESK HSDHMFSDKS 540
PSPDLWTSEQ NPPYSYYLYY MYANIMVLNN LRRERGLSTF LFRPHCGEAG SITHLVSAFL 600
TADNISHGLL LKKSPVLQYL YYLAQIPIAM SPLSNNSLFL EYSKNPLREF LHKGLHVSLS 660
TDDPMQFHYT KEALMEEYAI AAQVWKLSTC DLCEIARNSV LQSGLSHQEK QKFLGQNYYK 720
EGPEGNDIRK TNVAQIRMAF RYETLCNELS FLSDAMKSEE ITALTK 767
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0546--Nucleotide metabolism
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0862--Zinc
Interpro

IPR006650--A/AMP_deam_AS
IPR001365--A/AMP_deaminase_dom
IPR006329--AMPD
IPR029771--AMPD3
IPR032466--Metal_Hydrolase
PROSITE

PS00485--A_DEAMINASE
Pfam

PF00962--A_deaminase
Gene Ontology

GO:0003876--F:AMP deaminase activity
GO:0046872--F:metal ion binding
GO:0046031--P:ADP metabolic process
GO:0046033--P:AMP metabolic process
GO:0046034--P:ATP metabolic process
GO:0097009--P:energy homeostasis
GO:0034101--P:erythrocyte homeostasis
GO:0046039--P:GTP metabolic process
GO:0006188--P:IMP biosynthetic process
GO:0032264--P:IMP salvage