dbPAF Protein Information
| Tag | Content | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0000333 | ||||||||||||||||
| Uniprot Accession | O08705; NTCP_MOUSE; Q52L86; | ||||||||||||||||
| Genbank Protein ID | NP_001171032.1; XP_006515696.1; | ||||||||||||||||
| Genbank Nucleotide ID | NM_001177561.1; XM_006515633.2; | ||||||||||||||||
| Protein Name | Sodium/bile acid cotransporter | ||||||||||||||||
| Protein Synonyms/Alias | Na(+)/bile acid cotransporter;Na(+)/taurocholate transport protein;Sodium/taurocholate cotransporting polypeptide;Solute carrier family 10 member 1; | ||||||||||||||||
| Gene Name | Slc10a1 | ||||||||||||||||
| Gene Synonyms/Alias | Ntcp; | ||||||||||||||||
| Organism | Mus musculus(Mouse) | ||||||||||||||||
| NCBI Taxa ID | 10090 | ||||||||||||||||
| Functional Description (View all) |
The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium. | ||||||||||||||||
| Phosphorylation Sites |
dbPAF PTMs: 3
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| Sequence (Fasta) | MEAHNVSAPF NFSLPPGFGH RATDTALSVI LVVMLLLIML SLGCTMEFSK IKAHFWKPKG 60 VIIAIVAQYG IMPLSAFLLG KVFHLTSIEA LAILICGCSP GGNLSNLFTL AMKGDMNLSI 120 VMTTCSSFTA LGMMPLLLYI YSKGIYDGDL KDKVPYKGIM LSLVMVLIPC AIGIFLKSKR 180 PHYVPYVLKA GMIITFSLSV AVTVLSVINV GNSIMFVMTP HLLATSSLMP FTGFLMGYIL 240 SALFRLNPSC RRTISMETGF QNVQLCSTIL NVTFPPEVIG PLFFFPLLYM IFQLAEGLLF 300 IIIFRCYLKI KPQKDQTKIT YKAAATEDAT PAALEKGTHN GNNPPTQPGL SPNGLNSGQM 360 AN 363 |
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| Keyword | KW-0181--Complete proteome |
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| Interpro | IPR002657--BilAc:Na_symport/Acr3 |
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| PROSITE | |||||||||||||||||
| Pfam | PF01758--SBF |
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| Gene Ontology | GO:0016323--C:basolateral plasma membrane |