dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000327
Uniprot Accession O08691; ARGI2_MOUSE;
Genbank Protein ID NP_033835.1;
Genbank Nucleotide ID NM_009705.3;
Protein Name Arginase-2, mitochondrial
Protein Synonyms/Alias Kidney-type arginase;Non-hepatic arginase;Type II arginase;
Gene Name Arg2
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)		 May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis.
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
212EHFILKNYDIQYFSMdbPTM 3.0;PhosphoSitePlus20495213; 16381945; 23193290; 22135298
341YDHLPTPSSPHESENcurated21743459
Sequence
(Fasta)		MFLRSSASRL LHGQIPCVLT RSVHSVAIVG APFSRGQKKL GVEYGPAAIR EAGLLKRLSR 60
LGCHLKDFGD LSFTNVPQDD PYNNLVVYPR SVGLANQELA EVVSRAVSGG YSCVTMGGDH 120
SLAIGTIIGH ARHRPDLCVI WVDAHADINT PLTTVSGNIH GQPLSFLIKE LQDKVPQLPG 180
FSWIKPCLSP PNIVYIGLRD VEPPEHFILK NYDIQYFSMR EIDRLGIQKV MEQTFDRLIG 240
KRQRPIHLSF DIDAFDPKLA PATGTPVVGG LTYREGVYIT EEIHNTGLLS ALDLVEVNPH 300
LATSEEEAKA TARLAVDVIA SSFGQTREGG HIVYDHLPTP SSPHESENEE CVRI 355
Keyword

KW-0056--Arginine metabolism
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0378--Hydrolase
KW-0464--Manganese
KW-0479--Metal-binding
KW-0496--Mitochondrion
KW-1185--Reference proteome
KW-0809--Transit peptide
KW-0835--Urea cycle
Interpro

IPR014033--Arginase
IPR006035--Ureohydrolase
IPR023696--Ureohydrolase_domain
IPR020855--Ureohydrolase_Mn_BS
PROSITE

PS01053--ARGINASE_1
PS51409--ARGINASE_2
Pfam

PF00491--Arginase
Gene Ontology

GO:0005739--C:mitochondrion
GO:0004053--F:arginase activity
GO:0046872--F:metal ion binding
GO:0006525--P:arginine metabolic process
GO:0006941--P:striated muscle contraction
GO:0000050--P:urea cycle
GO:0001657--P:ureteric bud development