dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000325
Uniprot Accession O08688; CAN5_MOUSE; Q91YU0;
Genbank Protein ID NP_001288179.1; NP_031628.1; XP_011239963.1; XP_011239964.1; XP_011239965.1; XP_011239966.1; XP_011239967.1;
Genbank Nucleotide ID NM_001301250.1; NM_007602.4; XM_011241661.1; XM_011241662.1; XM_011241663.1; XM_011241664.1; XM_011241665.1;
Protein Name Calpain-5
Protein Synonyms/Alias New calpain 3;nCL-3;
Gene Name Capn5
Gene Synonyms/Alias Ncl3;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
40PATDDSLYYKGTPGPPhosphoSitePlus22135298
41ATDDSLYYKGTPGPTdbPTM 3.0;PhosphoPep 2.0;PhosphoSitePlus;curated21183079; 16381945; 23193290; 19060867; 22135298; 22817900
44DSLYYKGTPGPTVRWdbPTM 3.0;PhosphoPep 2.0;PhosphoSitePlus;curated21183079; 16381945; 23193290; 19060867; 22135298; 22817900;
621DRSSRQPSDLPGIVAdbPTM 3.0;PhosphoSitePlus;curated21183079; 16381945; 23193290; 22135298; 22817900
Sequence
(Fasta)
MFSCAKAYED QNYSALKRAC LRKKVLFEDP LFPATDDSLY YKGTPGPTVR WKRPKDICDD 60
PRLFVDGISS HDLHQGQVGN CWFVAACSSL ASRESLWQKV IPDWKEQEWN PEKPDSYAGI 120
FHFNFWRFGE WVDVIVDDRL PTVNNQLIYC HSNSKNEFWC ALVEKAYAKL AGCYQALDGG 180
NTADALVDFT GGVSEPIDLT EGDLATDEAK RNQLFERVLK VHSRGGLISA SIKAVTAADM 240
EARLACGLVK GHAYAVTDVR KVRLGHGLLA FFKSEKLDMI RLRNPWGERE WTGPWSDTSE 300
EWQKVSKSER EKMGVTVQDD GEFWMTFEDM CRYFTDIIKC RLINTSYLSI HKTWEEARLH 360
GAWTRHEDPQ QNRSGGCINH KDTFFQNPQY VFEVKKPEDE VLISIQQRPK RSTRREGKGE 420
NLAIGFDIYK VEENRQYRMH SLQHKAASSI YINSRSVFLR TELPEGRYVI IPTTFEPGHT 480
GEFLLRVFTD VPSNCRELRL DEPPRTCWSS LCGYPQQVAQ VHVLGAAGLK DSPTGANSYV 540
IIKCEGEKVR SAVQRGTSTP EYNVKGIFYR KKLAQPITVQ VWNHRVLKDE FLGQVHLKTA 600
PDDLQDLHTL HLQDRSSRQP SDLPGIVAVR VLCSASLTAV 641
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0621--Polymorphism
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease

Interpro

IPR000008--C2_dom
IPR022684--Calpain_cysteine_protease
IPR022682--Calpain_domain_III
IPR022683--Calpain_III
IPR000169--Pept_cys_AS
IPR001300--Peptidase_C2_calpain_cat

PROSITE

PS50203--CALPAIN_CAT
PS00139--THIOL_PROTEASE_CYS

Pfam

PF00168--C2
PF01067--Calpain_III
PF00648--Peptidase_C2

Gene Ontology

GO:0009986--C:cell surface
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0004198--F:calcium-dependent cysteine-type endopeptidase activity
GO:0060014--P:granulosa cell differentiation
GO:0001553--P:luteinization
GO:0001541--P:ovarian follicle development
GO:0006508--P:proteolysis