| Tag |
Content |
| dbPAF ID |
dbPAF-0000324 |
| Uniprot Accession |
O08686; BARX2_MOUSE; Q80ZF9; Q921G1;
|
| Genbank Protein ID |
NP_038828.2;
|
| Genbank Nucleotide ID |
NM_013800.2;
|
| Protein Name |
Homeobox protein BarH-like 2 |
| Protein Synonyms/Alias |
|
| Gene Name |
Barx2 |
| Gene Synonyms/Alias |
|
| Organism |
Mus musculus(Mouse) |
| NCBI Taxa ID |
10090 |
Functional Description
(View all) |
Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system. May be involved in controlling adhesive processes in keratinizing epithelia.Functional Description
Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system. May be involved in controlling adhesive processes in keratinizing epithelia. |
Phosphorylation Sites
|
dbPAF PTMs: 4 |
Sequence
(Fasta) | MHCHAELRLS SPGQLKAARR RYKTFMIDEI LSKETCDYFE KLSLYSVCPS LVVRPKPLHS 60
CTGSPSLRAY PLLSVITRQP TVISHLVPTG SGLTPVLTRH PVAAAEAAAA AAETPGGEAL 120
ASSESETEQP TPRQKKPRRS RTIFTELQLM GLEKKFQKQK YLSTPDRLDL AQSLGLTQLQ 180
VKTWYQNRRM KWKKMVLKGG QEAPTKPKGR PKKNSIPTSE EIEAEEKMNS QAQSQELLES 240
SERQEEPCDT QEPKACLVPL EVAEPIHQPQ ELSEASSEPP PLS
284Fasta Sequence
>O08686|Barx2|Mus musculus(Mouse)
MHCHAELRLSSPGQLKAARRRYKTFMIDEILSKETCDYFEKLSLYSVCPSLVVRPKPLHSCTGSPSLRAYPLLSVITRQPTVISHLVPTGSGLTPVLTRHPVAAAEAAAAAAETPGGEALASSESETEQPTPRQKKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQEAPTKPKGRPKKNSIPTSEEIEAEEKMNSQAQSQELLESSERQEEPCDTQEPKACLVPLEVAEPIHQPQELSEASSEPPPLS
|
| Keyword |
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0371--Homeobox
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
|
| Interpro |
IPR017970--Homeobox_CS
IPR001356--Homeobox_dom
IPR020479--Homeobox_metazoa
IPR009057--Homeodomain-like
IPR000047--HTH_motif
|
| PROSITE |
PS00027--HOMEOBOX_1
PS50071--HOMEOBOX_2
|
| Pfam |
PF00046--Homeobox
|
| Gene Ontology |
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0005667--C:transcription factor complex
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0001228--F:transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0001502--P:cartilage condensation
GO:0014902--P:myotube differentiation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006366--P:transcription from RNA polymerase II promoter
|
