dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000320
Uniprot Accession O08675; PAR3_MOUSE; B9EIT2; Q3UXV3;
Genbank Protein ID NP_034300.3;
Genbank Nucleotide ID NM_010170.4;
Protein Name Proteinase-activated receptor 3
Protein Synonyms/Alias
Gene Name F2rl2
Gene Synonyms/Alias Par3;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)		 High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
200ATAHPFTYQKLPKRSPhosphoSitePlus;curated22135298; 22817900
Sequence
(Fasta)		MKILILVAAG LLFLPVTVCQ SGINVSDNSA KPTLTIKSFN GGPQNTFEEF PLSDIEGWTG 60
ATTTIKAECP EDSISTLHVN NATIGYLRSS LSTQVIPAIY ILLFVVGVPA NIVTLWKLSL 120
RTKSISLVIF HTNLAIADLL FCVTLPFKIA YHLNGNNWVF GEVTCRITTV VFYGNMYCAI 180
LILTCMGINR YLATAHPFTY QKLPKRSFSM LMCGMVWVMV FLYMLPFVIL KQEYHLVHSE 240
ITTCHDVVDA CESPSSFRFY YFVSLAFFGF LIPFVIIIFC YTTLIHKLKS KDRIWLGYIK 300
AVLLILVIFT ICFAPTNIIL VIHHANYYYH NTDSLYFMYL IALCLGSLNS CLDPFLYFVM 360
SKVVDQLNP
Keyword

KW-0002--3D-structure
KW-0094--Blood coagulation
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0297--G-protein coupled receptor
KW-0325--Glycoprotein
KW-0356--Hemostasis
KW-0472--Membrane
KW-0675--Receptor
KW-1185--Reference proteome
KW-0732--Signal
KW-0807--Transducer
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR000276--GPCR_Rhodpsn
IPR017452--GPCR_Rhodpsn_7TM
IPR003943--Prot_act_rcpt_3
IPR003912--Protea_act_rcpt
PROSITE

PS50262--G_PROTEIN_RECEP_F1_2
Pfam

PF00001--7tm_1
Gene Ontology

GO:0016324--C:apical plasma membrane
GO:0016021--C:integral component of membrane
GO:0015057--F:thrombin receptor activity
GO:0007596--P:blood coagulation