dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000318
Uniprot Accession O08672; KIFC2_MOUSE; O08613;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Kinesin-like protein KIFC2
Protein Synonyms/Alias
Gene Name Kifc2
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
May play a role in microtubule-dependent retrograde axonal transport. May function as the motor for the transport of multivesicular body (MVB)-like organelles in dendrites.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
643VWKAGVASPVQRDPNdbPTM 3.0;PHOSIDA;PhosphoSitePlus;curated20415495; 16381945; 23193290; 21081558; 22135298; 22817900;
Sequence
(Fasta)
MYAFYSLLIY IFYSLFRRDG GAAAVSDPGD PTQKSGGQPR GRRRPDQFTS ELWSELNSLA 60
GCSESEDGQK GAEGGAAEVS LEEALMRLAE FLSVQLGAEE SCGTTPDLGK PGEVPPLLTV 120
TSQLLALLAW TRSPRGRQAL LQGTQPTCPV QPSTLDGSLS QEESSSQPTP ILDEVPRDET 180
QEHQPLQLEE EQRVWQRLEQ LILGQLEELR QQLEQQEEEL SRLRLGVGVT DSEKRVQHLT 240
LENEALKQSL SLTRDLLLHW GPGPLPRLSQ EEAGALLELQ GQLQEAQDTT EALRVQLGAQ 300
ELQLQGLRGA LRQLQQETEQ NCRQELQQVH GQLAGLRARM ASLRQGCGDL RGLVSTFTQS 360
CQGSLSEAQG QVSWALGALS AGKAKTQLSE GNQAPPTGCS GRLLELKGNI RVLCRLRPAE 420
GQPSSLVSVE PGQGGTITTC YRGRQHCFRL DWVFPQDASQ EEVFRQLEPA VLSCLQGYSV 480
CIFTYGQTGT GKTYSMEGPP EDPGIAPRAL QLLFREMGTG GHHHVTLSMV EIYNEAVRDL 540
LATGPPERLV VRQGPAGQGG IQVAGLTHWD VPNLETLHQM LSLGRSNRAT AATVMNQHSS 600
RSHALVTLTL RAASPPRPQG ITGTLHLVDL AGSERVWKAG VASPVQRDPN GARRLREAQA 660
INRSLLALGG VMAALRARRP HVPFRDSQLT RLLQPALWAG TTAVLLLQIS TRAEDLGETI 720
CSLKFAERVG QVELGPARRR RAPRSGTPSS LSTDTPLTGT SCTPTPSPGS PPSTSPNSCS 780
GLTLEPPGDP PP 793
Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR027640--Kinesin-like_fam
IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2

Pfam

PF00225--Kinesin

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005871--C:kinesin complex
GO:0005874--C:microtubule
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement