Tag |
Content |
dbPAF ID |
dbPAF-0000310 |
Uniprot Accession |
O08651; SERA_RAT; Q546Q9; |
Genbank Protein ID |
NP_113808.1; XP_006233072.1; |
Genbank Nucleotide ID |
NM_031620.1; XM_006233010.1; |
Protein Name |
D-3-phosphoglycerate dehydrogenase |
Protein Synonyms/Alias |
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Gene Name |
Phgdh |
Gene Synonyms/Alias |
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Organism |
Rattus norvegicus(Rat) |
NCBI Taxa ID |
10116 |
Functional Description (View all) |
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Phosphorylation Sites
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dbPAF PTMs: 7 Position | Peptides | Source | References ( PMIDs ) |
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14 | RKILISDSLDPCCRK | curated | 23984901 | 78 | QVVGRAGTGVDNVDL | PhosphoSitePlus | 22135298 | 147 | GTELNGKTLGILGLG | curated | 23984901 | 287 | SCPHLGASTKEAQSR | curated | 23984901 | 326 | QALTSAFSPHTKPWI | curated | 23984901 | 362 | QVVTQGTSLKNAGTC | curated | 23984901 | 371 | KNAGTCLSPAVIVGL | curated | 23984901 |
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Sequence (Fasta) | MAFANLRKIL ISDSLDPCCR KILQDGGLQV VEKQNLSKEE LIAELQDCEG LIVRSATKVT 60 ADVINAAEKL QVVGRAGTGV DNVDLEAATR KGVLVMNTPN GNSLSAAELT CGMLMCLARQ 120 IPQATASMKD GKWDRKKFMG TELNGKTLGI LGLGRIGREV AARMQAFGMK TVGYDPIISP 180 EVAASFGVQQ LPLEEIWPLC DFITVHTPLL PSTTGLLNDS TFAQCKKGVR VVNCARGGIV 240 DEGALLRALQ SGQCAGAALD VFTEEPPRDR ALVDHENVIS CPHLGASTKE AQSRCGEEIA 300 VQFVDMVKGK SLTGVVNAQA LTSAFSPHTK PWIGLAEALG TLMHAWAGSP KGTIQVVTQG 360 TSLKNAGTCL SPAVIVGLLR EASKQADVNL VNAKLLVKEA GLNVTTSHSP GVPGEQGIGE 420 CLLTVALAGA PYQAVGLVQG TTPMLQMLNG AVFRPEVPLR RGQPLLLFRA QPSDPVMLPT 480 MIGLLAEAGV QLLSYQTSKV SDGDTWHVMG LSSLLPSLDA WKQHVSEAFQ FCF
534Fasta Sequence
>O08651|Phgdh|Rattus norvegicus(Rat) MAFANLRKILISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGVLVMNTPNGNSLSAAELTCGMLMCLARQIPQATASMKDGKWDRKKFMGTELNGKTLGILGLGRIGREVAARMQAFGMKTVGYDPIISPEVAASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMHAWAGSPKGTIQVVTQGTSLKNAGTCLSPAVIVGLLREASKQADVNLVNAKLLVKEAGLNVTTSHSPGVPGEQGIGECLLTVALAGAPYQAVGLVQGTTPMLQMLNGAVFRPEVPLRRGQPLLLFRAQPSDPVMLPTMIGLLAEAGVQLLSYQTSKVSDGDTWHVMGLSSLLPSLDAWKQHVSEAFQFCF
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Keyword |
KW-0007--Acetylation KW-0028--Amino-acid biosynthesis KW-0181--Complete proteome KW-0903--Direct protein sequencing KW-0520--NAD KW-0560--Oxidoreductase KW-0597--Phosphoprotein KW-1185--Reference proteome KW-0718--Serine biosynthesis
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Interpro |
IPR029009--ASB_dom IPR006139--D-isomer_2_OHA_DH_cat_dom IPR029753--D-isomer_DH_CS IPR029752--D-isomer_DH_CS1 IPR006140--D-isomer_DH_NAD-bd IPR016040--NAD(P)-bd_dom IPR006236--PGDH
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PROSITE |
PS00065--D_2_HYDROXYACID_DH_1 PS00670--D_2_HYDROXYACID_DH_2 PS00671--D_2_HYDROXYACID_DH_3
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Pfam |
PF00389--2-Hacid_dh PF02826--2-Hacid_dh_C
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Gene Ontology |
GO:0070062--C:extracellular exosome GO:0043209--C:myelin sheath GO:0051287--F:NAD binding GO:0004617--F:phosphoglycerate dehydrogenase activity GO:0070314--P:G1 to G0 transition GO:0009448--P:gamma-aminobutyric acid metabolic process GO:0021782--P:glial cell development GO:0006541--P:glutamine metabolic process GO:0006544--P:glycine metabolic process GO:0006564--P:L-serine biosynthetic process GO:0021915--P:neural tube development GO:0031175--P:neuron projection development GO:0010468--P:regulation of gene expression GO:0009070--P:serine family amino acid biosynthetic process GO:0021510--P:spinal cord development GO:0019530--P:taurine metabolic process GO:0006566--P:threonine metabolic process
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