dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000310
Uniprot Accession O08651; SERA_RAT; Q546Q9;
Genbank Protein ID NP_113808.1; XP_006233072.1;
Genbank Nucleotide ID NM_031620.1; XM_006233010.1;
Protein Name D-3-phosphoglycerate dehydrogenase
Protein Synonyms/Alias
Gene Name Phgdh
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
14RKILISDSLDPCCRKcurated23984901
78QVVGRAGTGVDNVDLPhosphoSitePlus22135298
147GTELNGKTLGILGLGcurated23984901
287SCPHLGASTKEAQSRcurated23984901
326QALTSAFSPHTKPWIcurated23984901
362QVVTQGTSLKNAGTCcurated23984901
371KNAGTCLSPAVIVGLcurated23984901
Sequence
(Fasta)
MAFANLRKIL ISDSLDPCCR KILQDGGLQV VEKQNLSKEE LIAELQDCEG LIVRSATKVT 60
ADVINAAEKL QVVGRAGTGV DNVDLEAATR KGVLVMNTPN GNSLSAAELT CGMLMCLARQ 120
IPQATASMKD GKWDRKKFMG TELNGKTLGI LGLGRIGREV AARMQAFGMK TVGYDPIISP 180
EVAASFGVQQ LPLEEIWPLC DFITVHTPLL PSTTGLLNDS TFAQCKKGVR VVNCARGGIV 240
DEGALLRALQ SGQCAGAALD VFTEEPPRDR ALVDHENVIS CPHLGASTKE AQSRCGEEIA 300
VQFVDMVKGK SLTGVVNAQA LTSAFSPHTK PWIGLAEALG TLMHAWAGSP KGTIQVVTQG 360
TSLKNAGTCL SPAVIVGLLR EASKQADVNL VNAKLLVKEA GLNVTTSHSP GVPGEQGIGE 420
CLLTVALAGA PYQAVGLVQG TTPMLQMLNG AVFRPEVPLR RGQPLLLFRA QPSDPVMLPT 480
MIGLLAEAGV QLLSYQTSKV SDGDTWHVMG LSSLLPSLDA WKQHVSEAFQ FCF 534
Keyword

KW-0007--Acetylation
KW-0028--Amino-acid biosynthesis
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0520--NAD
KW-0560--Oxidoreductase
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0718--Serine biosynthesis

Interpro

IPR029009--ASB_dom
IPR006139--D-isomer_2_OHA_DH_cat_dom
IPR029753--D-isomer_DH_CS
IPR029752--D-isomer_DH_CS1
IPR006140--D-isomer_DH_NAD-bd
IPR016040--NAD(P)-bd_dom
IPR006236--PGDH

PROSITE

PS00065--D_2_HYDROXYACID_DH_1
PS00670--D_2_HYDROXYACID_DH_2
PS00671--D_2_HYDROXYACID_DH_3

Pfam

PF00389--2-Hacid_dh
PF02826--2-Hacid_dh_C

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0051287--F:NAD binding
GO:0004617--F:phosphoglycerate dehydrogenase activity
GO:0070314--P:G1 to G0 transition
GO:0009448--P:gamma-aminobutyric acid metabolic process
GO:0021782--P:glial cell development
GO:0006541--P:glutamine metabolic process
GO:0006544--P:glycine metabolic process
GO:0006564--P:L-serine biosynthetic process
GO:0021915--P:neural tube development
GO:0031175--P:neuron projection development
GO:0010468--P:regulation of gene expression
GO:0009070--P:serine family amino acid biosynthetic process
GO:0021510--P:spinal cord development
GO:0019530--P:taurine metabolic process
GO:0006566--P:threonine metabolic process