dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000301
Uniprot Accession O08618; KPRB_RAT;
Genbank Protein ID NP_476472.1; XP_006246496.1; XP_006246497.1; XP_006246498.1; XP_006246499.1; XP_006246500.1;
Genbank Nucleotide ID NM_057131.1; XM_006246434.2; XM_006246435.2; XM_006246436.2; XM_006246437.2; XM_006246438.2;
Protein Name Phosphoribosyl pyrophosphate synthase-associated protein 2
Protein Synonyms/Alias
Gene Name Prpsap2
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
219GEAQDAESDLVDGRHcurated23712012
227DLVDGRHSPPMVRSVPhosphoSitePlus;UniProt;curated22135298; 22673903; 25532521; 23712012; 21630457; 23589303;
233HSPPMVRSVAAIHPScurated23984901
Sequence
(Fasta)		MFCVAPPELE TKMNITKGGL VLFSANSNSS CMELSKKIAE RLGVEMGKVQ VYQEPNRETR 60
VQIQESVRGK DVFIIQTVSK DVNTTIMELL IMVYACKTSC AKSIIGVIPY FPYSKQCKMR 120
KRGSIVSKLL ASMMCKAGLT HLITMDLHQK EIQGFFNIPV DNLRASPFLL QYIQEEIPDY 180
RNAVIVAKSP ASAKRAQSFA ERLRLGIAVI HGEAQDAESD LVDGRHSPPM VRSVAAIHPS 240
LEIPMLIPKE KPPITVVGDV GGRIAIIVDD IIDDVDSFLA AAETLKERGA YKIFVMATHG 300
LLSSDAPRLI EESAIDEVVV TNTIPHEIQK LQCPKIKTVD ISMILSEAIR RIHNGESMSY 360
LFRNIGLDD
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0545--Nucleotide biosynthesis
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR029099--Pribosyltran_N
IPR029057--PRTase-like
IPR005946--Rib-P_diPkinase
PROSITE
Pfam

PF14572--Pribosyl_synth
PF13793--Pribosyltran_N
Gene Ontology

GO:0043234--C:protein complex
GO:0002189--C:ribose phosphate diphosphokinase complex
GO:0000287--F:magnesium ion binding
GO:0004749--F:ribose phosphate diphosphokinase activity
GO:0060348--P:bone development
GO:0009165--P:nucleotide biosynthetic process