dbPAF Protein Information
Tag | Content | ||||||||
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dbPAF ID | dbPAF-0000291 | ||||||||
Uniprot Accession | O08593; PDE7A_RAT; | ||||||||
Genbank Protein ID | |||||||||
Genbank Nucleotide ID | |||||||||
Protein Name | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | ||||||||
Protein Synonyms/Alias | Rolipram-insensitive phosphodiesterase type 7; | ||||||||
Gene Name | Pde7a | ||||||||
Gene Synonyms/Alias | |||||||||
Organism | Rattus norvegicus(Rat) | ||||||||
NCBI Taxa ID | 10116 | ||||||||
Functional Description (View all) |
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction (By similarity). | ||||||||
Phosphorylation Sites |
dbPAF PTMs: 1
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Sequence (Fasta) | DQTALYIRML GDVRVRSRAG FETERRGSHP YIDFRIFHAQ SEIEASVSAR NIRRLLSFQR 60 YLRSSRFFRG ATVCRSLNIL DEDYNGQAKC MLEKVGNWNF DIFLFDRLTN GNSLVSLTFH 120 LFSLHGLIEY FHLDMVKLRR FLVMIQEDYH SQNPYHNAVH AADVTQAMHC YLKEPKLANS 180 VTPWDILLSL IAAATHDLDH PGVNQPFLIK TNHYLATLYK NTSVLENHHW RSAVGLLRES 240 GLFSHLPLES RHEMEAQIGA LILATDISRQ NEYLSLFRSH LDKGDLHLDD GRHRHLVLQM 300 ALKCADICNP CRNWELSKQW SEKVTEEFFH QGDIEKKYHL GVSPLCDRQT ESIANIQIGF 360 MTYLQEPLFT EWARFSDTRL SQTMLGHVGL NKASWKGLQR QQPSSEDASA AFELNSQLLT 420 QENRLS 427 |
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Keyword | KW-0114--cAMP |
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Interpro | IPR003607--HD/PDEase_dom |
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PROSITE | PS00126--PDEASE_I |
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Pfam | PF00233--PDEase_I |
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Gene Ontology | GO:0004115--F:3',5'-cyclic-AMP phosphodiesterase activity |