dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000267
Uniprot Accession O08547; SC22B_MOUSE; Q91VU3;
Genbank Protein ID NP_035472.1;
Genbank Nucleotide ID NM_011342.4;
Protein Name Vesicle-trafficking protein SEC22b
Protein Synonyms/Alias ER-Golgi SNARE of 24 kDa;ERS-24;ERS24;SEC22 vesicle-trafficking protein homolog B;SEC22 vesicle-trafficking protein-like 1;mSec22b;
Gene Name Sec22b
Gene Synonyms/Alias Sec22l1;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)		 SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
26SMQEDEQSGRDLQQYcurated25338131
35RDLQQYQSQAKQLFRcurated21183079
50KLNEQSPTRCTLEAGdbPTM 3.0;PhosphoSitePlus;curated19854140; 16381945; 23193290; 22135298; 22817900
137RARRNLGSINTELQDdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated17114649; 18630941; 19144319; 19367708; 16381945; 23193290;
140RNLGSINTELQDVQRPHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;curated21081558; 19060867; 22135298; 25266776
168EALSALDSKANNLSSdbPTM 3.0;Phospho.ELM 9.0;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated17242355; 16381945; 23193290; 21183079; 19060867; 22135298;
174DSKANNLSSLSKKYRPhosphoPep 2.0;curated19060867; 25338131
175SKANNLSSLSKKYRQdbPTM 3.0;PhosphoSitePlus;curated21183079; 16381945; 23193290; 22135298; 22817900; 23984901;
177ANNLSSLSKKYRQDAdbPTM 3.0;PhosphoSitePlus;curated19854140; 21183079; 16381945; 23193290; 22135298; 25266776;
Sequence
(Fasta)		MVLLTMIARV ADGLPLAASM QEDEQSGRDL QQYQSQAKQL FRKLNEQSPT RCTLEAGAMT 60
FHYIIEQGVC YLVLCEAAFP KKLAFAYLED LHSEFDEQHG KKVPTVSRPY SFIEFDTFIQ 120
KTKKLYIDSR ARRNLGSINT ELQDVQRIMV ANIEEVLQRG EALSALDSKA NNLSSLSKKY 180
RQDAKYLNMR STYAKLAAVA VFFIMLIVYV RFWWL 216
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0256--Endoplasmic reticulum
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
Interpro

IPR011012--Longin-like_dom
IPR010908--Longin_dom
IPR001388--Synaptobrevin
PROSITE

PS50859--LONGIN
PS50892--V_SNARE
Pfam

PF13774--Longin
PF00957--Synaptobrevin
Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0005793--C:endoplasmic reticulum-Golgi intermediate compartment
GO:0033116--C:endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0042470--C:melanosome
GO:0031201--C:SNARE complex
GO:0005484--F:SNAP receptor activity
GO:0000149--F:SNARE binding
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0045732--P:positive regulation of protein catabolic process
GO:0015031--P:protein transport
GO:0033043--P:regulation of organelle organization
GO:0048280--P:vesicle fusion with Golgi apparatus
GO:0016192--P:vesicle-mediated transport