dbPAF Protein Information
| Tag | Content | ||||||||||||||||
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| dbPAF ID | dbPAF-0000265 | ||||||||||||||||
| Uniprot Accession | O08542; EFNA4_MOUSE; O55218; | ||||||||||||||||
| Genbank Protein ID | NP_031936.2; | ||||||||||||||||
| Genbank Nucleotide ID | NM_007910.2; | ||||||||||||||||
| Protein Name | Ephrin-A4 | ||||||||||||||||
| Protein Synonyms/Alias | EPH-related receptor tyrosine kinase ligand 4;LERK-4; | ||||||||||||||||
| Gene Name | Efna4 | ||||||||||||||||
| Gene Synonyms/Alias | Epl4;Eplg4;Lerk4; | ||||||||||||||||
| Organism | Mus musculus(Mouse) | ||||||||||||||||
| NCBI Taxa ID | 10090 | ||||||||||||||||
| Functional Description (View all) |
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils (By similarity). | ||||||||||||||||
| Phosphorylation Sites |
dbPAF PTMs: 3
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| Sequence (Fasta) | MRLLPLLRTV LWAALLGSRL PGCSSLRHPI YWNSSNPRLL RGDAVVELGF NDYLDIFCPH 60 YESPGPPEGP ETFALYMVDW SGYEACTAEG ANAFQRWNCS MPFAPFSPVR FSEKIQRYTP 120 FPLGFEFLPG ETYYYISVPT PESPGRCLRL QVSVCCKESG SSHESAHPVG SPGESGTSGW 180 RGGHAPSPLC LLLLLLLPIL RLLRVL 207 |
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| Keyword | KW-1003--Cell membrane |
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| Interpro | IPR008972--Cupredoxin |
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| PROSITE | |||||||||||||||||
| Pfam | PF00812--Ephrin |
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| Gene Ontology | GO:0031225--C:anchored component of membrane |