dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000252
Uniprot Accession O02482; UNC37_CAEEL; P91912;
Genbank Protein ID NP_491932.1;
Genbank Nucleotide ID NM_059531.6;
Protein Name Transcription factor unc-37
Protein Synonyms/Alias Uncoordinated protein 37;
Gene Name unc-37
Gene Synonyms/Alias esg;W02D3.9;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)
Transcription factor that functions with the neural specificity gene unc-4 to govern motor neuron identity.
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
203ANKNGRDSTNSVASSPhosphoPep 2.019060867
210STNSVASSGASTPSIPhosphoPep 2.019060867
Sequence
(Fasta)
MKASYLETLD RIKDEHAEMS KHVNQQRSDI EKVALEKENM NRSYMTYAEV SNTLRSDLRK 60
AEEINKRLQE FIMQSLAPQL SQDNQANCLA ALEAFKTASP RENGNGAPAL PPGFPPGAAG 120
MLGMMPNMPF GMSPAMSQLF NQFASPHVNG GDGAGGSSGG ASEAKKAKLE DPDDGELEID 180
VTNDDHPSTA SNGGAANKNG RDSTNSVASS GASTPSIASN SRARQQQQPL AGLQGLEQMN 240
FLAGFNPNLL RQASAAGGFN FLNDPHAQAR LAAAIGQIGS RPAYSFKIVD GGVPTPTSFP 300
PDAQKGPGIP TGLKKKMELN HGEVVCAATI SRDNSRVYTG GKGCVKIWDV KESDISGATV 360
VNRPPIASLD CLKENYIRSC KLFEDGNTLL IGGEASTVAL WDLTTETKTL DLETDSQACY 420
ALAMSPDEKL LFACLADGNI LIYDIHNKVK VGTLPGHQDG ASCLDLSKDG TKLWSGGLDN 480
SVRCWDLAQR KEVAKHDFAS QVFSLGCCPN DEWVAVGMEN NYVEVLSTTG KEKYQLTQHE 540
SCVLSLKFAH SGKFFISTGK DNALNAWRTP YGASLFQLKE NSSVLSCDIS FDDSLIVTGS 600
GEKKATLYAV EY 613
Keyword

KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0003714--F:transcription corepressor activity
GO:0008134--F:transcription factor binding
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0050770--P:regulation of axonogenesis
GO:0001505--P:regulation of neurotransmitter levels
GO:0050803--P:regulation of synapse structure or activity
GO:0007268--P:synaptic transmission
GO:0006351--P:transcription, DNA-templated