dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000221
Uniprot Accession O01971; EMR1_CAEEL;
Genbank Protein ID NP_490907.1;
Genbank Nucleotide ID NM_058506.5;
Protein Name Emerin homolog 1
Protein Synonyms/Alias Ce-emerin;
Gene Name emr-1
Gene Synonyms/Alias M01D7.6;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)		 Involved in chromosome segregation and cell division, probably via its interaction with lmn-1, the main component of nuclear lamina. Has some overlapping function with lem-2.
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
64NEDSLIISSSPKKSPcurated18806794
66DSLIISSSPKKSPPQdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;curated19530675; 16381945; 23193290; 21081558; 18806794
94TTSPESDSDDCEESMdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;curated19530675; 16381945; 23193290; 21081558; 19060867; 18806794
Sequence
(Fasta)		MDVSQLTDAE LRDSLKSHGV SVGPIVATTR KLYEKKLIKL SDGSINNQSN LNDSQFNEDS 60
LIISSSPKKS PPQRVFQNVS AATAAATTSP ESDSDDCEES MRYLTEEEMA ADRASARQAQ 120
SNKGGFLGST ITFTILFVFI AVFAYFLIEN AEQLKLVAET NPEDTI 167
Keyword

KW-0131--Cell cycle
KW-0181--Complete proteome
KW-0472--Membrane
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR011015--LEM/LEM-like_dom
IPR003887--LEM_dom
PROSITE

PS50954--LEM
Pfam

PF03020--LEM
Gene Ontology

GO:0005639--C:integral component of nuclear inner membrane
GO:0005635--C:nuclear envelope
GO:0005521--F:lamin binding
GO:0007059--P:chromosome segregation
GO:0000281--P:mitotic cytokinesis
GO:0010165--P:response to X-ray