dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000208
Uniprot Accession O01835; CPB3_CAEEL;
Genbank Protein ID NP_491680.2;
Genbank Nucleotide ID NM_059279.6;
Protein Name Cytoplasmic polyadenylation element-binding protein 3
Protein Synonyms/Alias
Gene Name cpb-3
Gene Synonyms/Alias B0414.5;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)
Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
45SVGEKSPTPATVYDLdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;curated19530675; 16381945; 23193290; 21081558; 18806794
Sequence
(Fasta)
MNLNDRVEGI GNERSIVAKS TERKNKIPPS LKLSPVESVG EKSPTPATVY DLFKKYHKSD 60
SVKPTEEDNM NVGFDKLSTD EKNGFLRKLQ MLTVGSKKSS KVDESTPSPA NRLLKKIVPS 120
RRTSTEHPNS SNRMHIFGSS RTTKKSIDSE RNSQRKKSAR RLNFERDAEQ KKDSTKTNNS 180
SFVAEMTREY EKIVISKGAP VPINKANRNL YRNPRGSLET PTDSPQKGFS SSTESSPSDS 240
MNQFPSREHF TSANEESPMK RKNFQQEHGN KNRDSDATWF GELPPRDYTS PTFSRKIFVG 300
GVPWDITEAA LKDSFGEFGS CAVEWPGQEA RYRSGQSNLA PSNGSLRAQT KYTGQAATGY 360
VYMIFEDERA VASLLHECSQ EIGGAGEWYF KIRAQRSKST EIRQVQIIPW VTSDSMFCED 420
DTLLETGIEP KRTVFVGALH GMMTAQVLHS IMEDCFGAVE CVQLDTDKFK YPIGSGRVTF 480
REHGAYFKAI EMGYLHVYTS KFRKRVQIDP FLESTCCMVC NSQSAHCFCR NKNCFKYYCH 540
NCWALDHGKD DDQEVHIPVI VPSSASKAFP GATTRRSQVS SSLSLKNGSN NSQVNNSIPH 600
FPSAGFPIIV GAPAQTLSAL YGYIQNGQQL LKPAVFEPPM TPSPSEINKN RRSFTEFSTP 660
PTVFFNSTPV ISPQKSVSDG SPLPAYYNSA AFLTPPPTYY GSPNHPTSSN ISQPQQPYYG 720
ANLYYGFIPP QQHPSAMMRS PNYGQ 746
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0694--RNA-binding

Interpro

IPR032296--CEBP_ZZ
IPR012677--Nucleotide-bd_a/b_plait
IPR000504--RRM_dom

PROSITE
Pfam

PF16366--CEBP_ZZ
PF16367--RRM_7

Gene Ontology

GO:0005737--C:cytoplasm
GO:1990124--C:messenger ribonucleoprotein complex
GO:0043005--C:neuron projection
GO:0005634--C:nucleus
GO:0045202--C:synapse
GO:0003730--F:mRNA 3'-UTR binding
GO:0000166--F:nucleotide binding
GO:0043022--F:ribosome binding
GO:0008135--F:translation factor activity, RNA binding
GO:0000900--F:translation repressor activity, nucleic acid binding
GO:2000766--P:negative regulation of cytoplasmic translation
GO:0006412--P:translation