dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000204
Uniprot Accession O01808; O01808_CAEEL;
Genbank Protein ID NP_491407.2;
Genbank Nucleotide ID NM_059006.2;
Protein Name UBR E3 ubiquitin ligase homolog
Protein Synonyms/Alias
Gene Name ubr-4
Gene Synonyms/Alias C44E4.1;CELE_C44E4.1;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
549TILKLKLTSEAEREPPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
1193KTKSRKRSTQNSVAVPhosphoPep 2.019060867
1194TKSRKRSTQNSVAVGPhosphoPep 2.019060867
Sequence
(Fasta)
MDPRETAIGL VRYVTENAAK DFDGESIAAI IYRLRVVENY VSSDVDIICE AMRILIKKLV 60
NLPPITFSPD VWMPIMTSIT EGAIEPQWRI MMESIDISKF SSTSSNFVHM DSITASSTKC 120
SEQITSICKG FALEFGLTRR LFSAIWNTDL EETARKMMNQ EWDSVKIDSS PDSAKQAAGL 180
IEKSIFDLFS EMKDHETFAN ELYYAALARI LKRLQENKKP AIQDSEDISF YESSLHIYDE 240
LIKKLWPHLS KKDPNVKKNT LIIFEKLISL SPTDVLVQRI TEKFIDSCEW LKISGEEICT 300
SMEPRLWKIV GSLVSRILDL KKTIPYEIDC GPDSFDSTCD QPSNMKERFL RHMVDSVWIL 360
IQITHFNTQK KYFQTRSSLL SIIQFLRTAK SSEEIVQFMR VFYPELVFGN ETLITHAAIE 420
MLRESASHHS IKADDFISIV LSVIDAPAIV RIIDVISCIK DEKVRKEAVE KTIIRMANDL 480
EDEDQKREGY VNHLHENGSF WNDIAKYADA SILDKAGKRF VEVSVDSMDI RSSVLATDIF 540
LTILKLKLTS EAEREPESCV ICNVSYSNIK IDLEKWNKMG NILVECNMVK RSKSEALPLF 600
TIHQLENIDL PMRDLVYVVT QMKFLDTKEG MELHRKFYDG LPGVNVIFEK FMSKSHKIEL 660
CMKLLDEFAK IIAINEKSLI FSLDHENILD WLEEIGVLDS PQITEKLVDI CFSIEVWDVL 720
TLLQLDGPEC HYWDLQMFGR FWKTSLMDLL DEKMMKKVNE KMGSILKEQY DKQSHVAKAT 780
REKRSNGKFP NRPKVADWEE QLLLMHNRIA GHLTKKKVED FADESTQKFT WLLGVCSGQM 840
SYKKEVAVDA EKILSRLYPD AEKRNEVLYH FGVSSILKGL DRPRGKFSRS LHILFMQIYL 900
DLVQIDSKSW KIDDSVQKLS RRLGGFNEWL MIVDEEKRED DGGFRIYIVL NLSHYFWELL 960
EGCKASQVVD AHAILKIRKF AEVLASILDK ITFWPNPKLH AYYYIAQFLE PLETIFHFPE 1020
IAEQNRKVIE SFFKQLFDKL LEQKYQEGLL QDTKLIIQKT DKYLSSSLNL FNEYNTQEPS 1080
KIYPVNEIFS LFCRYGSENV HLYCLKMIKK SLQTLASNIL EHEHILKGEV CIETELQKRL 1140
VCDAVLLTEF FGYFSCIYAQ VSENQPSEHD DVAKAFMLLD SDIHLKTKSR KRSTQNSVAV 1200
GSHRHQTAEN MDLNFCTYKS TGRAYVTQHW YNCYTCNMME SEGVCSVCAI NCHRGHDLAY 1260
SKKGSFFCDC GEKKCGAMQG IYHLPNSMYS LRGQLPEKNG DKTLPKIRNV FEHRFENLNS 1320
NCCDELKSAL NDVQEEFKEV QDDLEQILEA VDFANQKALQ VTEERLAVLE SFNDMDDVII 1380
SEKEKFIEPL ESGHFLPTRR DDLPVQELRV ASSQHKIREL SDIIKLDDGT ELLVLIPESI 1440
QTCLQLHYMD TRTNLIQGMH ALRTETEQIP FNARSLHVSG NRLVVCGQYE FFALRFSPQG 1500
DVIDRAHIKL LENGASSSMN NNPVVRAKFC REIESDKRRR QLIAVATMQY IRIYDLTLHE 1560
TNFVEEMVLP AGNVEDVEII NQEDGNVRIL VLSSSGYLYE HNISVFNAEN NSIFLTNVVN 1620
TPGMDMNGDG VSLHYSSTFN LLFVSLENGA FVAQLPEPTG NSTAPIYDWK HLNIKNPVDA 1680
WKETSGIIAC LSTNCNHQVN YFHPTVGKIL LQKTSVKRSI MTYFLMTSAK NQSVYSVLIY 1740
PNVPTCEIWE TSWNNVHDLW IDDVPTERYA VEVVEQKSTQ IPIDRDELVL LAEQCEQIRT 1800
VDWNCREIGM FYTHEELNNR LSSSDSLPIT LIQQTHFKLS ARITNFRQIV RMIRVEVEGN 1860
TGPEYLKIGT TRYSISSRGP KTFDLRLSRE ESLALDHRDI TIEVIPRSNQ NRVTLKSLRL 1920
LGCDRSAMDE IQPRYERQPI LTNSNKLVYS ILEFATLSGL EWAGNMAKKH LSRKLNHPAV 1980
CSVSTRAIVK CHPSVDEELF KIIDGAYLQE WKALIDWTES EGFGEMRLHH VEQLLDRMEA 2040
VRTRWPYFVK SLKREFGTVT SFVELMRNEM KRMPLHRCQM MAQAIVKIVF GLLSNGTNEA 2100
EQLIHVFLNI FTDQDTYHLA NDMRSAVQET ISRFENALKE EKKLMVEHEN MDKESVLRIK 2160
NYGFSPFYGA PRIIAKTPES MLIAKIAETI PIDSEENFKW LEQLISMILE KLTRSNSTVT 2220
WQNLSDSPSY NLSRVLASCL AICDPVIIRN HFSRLIHIIK YDVEKIFPMS EKSYSNYSLL 2280
RSVELLLFVC LEKRGDESKE NQEMLDSIVH DLQAVGIRNL CLKILEKVIP HWKDRGPSTF 2340
SRNSAESRKV WLPHVPLVSS SANPPNTSIM NWPSTSEDSY IIACTDLILL IPQHLQELDR 2400
RKSVPRDDQW IQKLCQLASL SSGCSAYRQC KKLLLAMCHN DENKYKIMRD KYKMQDLLQQ 2460
LVKKYLDVSK EVGGHQQLTE IVDVLASITK LALIRPDMWR DVCSTHTTWL LRLACYTTDV 2520
VASQVVELLI VAVRDSSVGG QLSIQLADSI VEAENGEFIE KIIKRFLIGR DEQLRWTLHG 2580
MLRSVIQLAS RQNQCILVKK LYNTIYPLAA NLGVQGAQLV DLIATYAPRV FSSTELVAMT 2640
QSEISTIEKI RNTLNGDGYQ GMYKLMSDLG LGWKSINFDR NPCLVCFTSK GSHDVVKMTS 2700
IKSDIRYSAN TIIYKLISNY EVSKVTIKLT ELKKSKSIKK VSLYYSAKSV ESVDLKLHPE 2760
LWRKCAMVTV AENETVINLS LAVPVVTSSL IVEFEEVVDH RGSSQLHCPR CTVPVRTHSG 2820
VCESCGENAF QCAKCRAINY VEKEPFLCQS CGFCKYAQIS LFVVCRALPG AQHITCDAER 2880
GQCVQEITQL LIKMETTKTK LTGYRAACES LYLRNRPLPP YKLHVENNHT SEFFDANGTM 2940
NIEQLPFQSI TMPMNNLAVA IRTLHSELCQ QTQQLMYLHE ELNRYDHASE VSVVFHKPQN 3000
ISYYSTGQSC FGCLCNQLLH SVALLHSSCD DENALNLILS SDSLIEKLGV LAQTYETLRE 3060
EVEELLVRLM FDRLDVTTKV EKLIHTGDIN LSVMVKSLMY AADPTWQQKL KLLIRLAMDK 3120
RDENCCLQAL MVLSKYLEAT KSVTLDERKK IKLTPNKNIT KWLTTDEEWK DCFSVASTST 3180
APTKSLPSNP YQWITDCLFS QWMSVRSAAN QLLVNLSRQQ FHEPVALLIL CENMSKLSDV 3240
PSSVCDQFMC SAHTIIDSSV NTKARLFVQQ FHVYLIKRIH EECAKLHEQS VNLLSDNMFG 3300
ERLRCFVELL SLLLSGSNVE NVLLKAGADD LLIFLLHSTI FLKRIMTRRT RATDSSRIAL 3360
EKLLKRVSCR DGTKLMSVCV ESLKLVKDTS TLGIIVGVMM EIMDPQQETE ESFLIQIEKD 3420
IAQEDFLQGR MTHNPYNSSD PGMGPLMRDI KNKICRDTEM IALMEDDNGM ELLVNGNIIS 3480
LSLSVRDVYD RLWKRSNNGS PMLIVYRMRG LMGDAVETFI ENFGVADNSE ADDEEDEQLV 3540
RMTHCLMECG GIDKLMDLLT TNVDSSSGSS RFLLCYLRKI FERIVKIPIG RKILVQRRMV 3600
ERMMSVIRTC CADPTNESKV LIGMELYKVV EFVVSDKHVQ DILGGIREDD AMWWFDLFEK 3660
RGNEEGSVTE LHRKTAQILD QMTMSIGNIV LGNDASEGVL VKMYEKVLKW EQIDSGAPPS 3720
GATDHQNRSR ITKKDQIMLM TEQLATITSN IISSAHGIRL KQKILDSGVI SSTCNYLTKD 3780
LPNLYQPTES PEWKVFLARP SLKLILTLLA GLARGHQASQ KEIAKTTLKL MHRLEQVASD 3840
NSIGTLAENV IEALNEDEEV RNQIKLVRDE TEKKKKQMAM LNREKQLTKM RMKVGTGGQI 3900
KVSSRTLHNE PSIDDSDSLP CCICRESVIS GDKSAGVYAF AAIDPDSGKT STVSMMVMVH 3960
FNCHKDAIRG GGGRAADEWT RSKLHNAGAK CNVITPISMG VVIGDAWIDA LHRFENDVGR 4020
VSGLAHGVVN RNFVFVDICN LIDRFIYKRS FSNQSEGGGR ESNMQYLAIL HLLGITLPAD 4080
AELEISAPNH RLIAFLFTEL TADSWNDQRN DVLRAGINDA QTNGAPATWD GFKPTLMTWA 4140
FVDAYFNKVI KITGEDRLEW LREHLVETIN KTRGFVDDFD SNILPCEDVA EFCDVTGAPI 4200
DDVNLFLAGG PPQ 4214
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR004190--DNA_pol_proc_fac
IPR025704--E3_Ub_ligase_UBR4
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02916--DNA_PPF
PF13764--E3_UbLigase_R4
PF02207--zf-UBR

Gene Ontology

GO:0008270--F:zinc ion binding
GO:0006260--P:DNA replication