dbPAF Protein Information
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dbPAF ID | dbPAF-0000198 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Uniprot Accession | O01761; UNC89_CAEEL; Q17362; Q5W614; Q5W615; Q5W616; Q5W617; Q646H5; Q64EQ8; Q7Z119; Q7Z120; | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Genbank Protein ID | NP_001020984.1; NP_001020985.1; NP_001020988.1; NP_001020989.1; NP_001020990.1; NP_001293453.1; NP_001293454.1; | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Genbank Nucleotide ID | NM_001025813.1; NM_001025814.2; NM_001025817.2; NM_001025818.1; NM_001025819.1; NM_001306524.1; NM_001306525.1; | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Name | Muscle M-line assembly protein unc-89 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Synonyms/Alias | Uncoordinated protein 89; | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Name | unc-89 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Synonyms/Alias | C09D1.1; | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Organism | Caenorhabditis elegans | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
NCBI Taxa ID | 6239 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Functional Description (View all) |
Structural component of the muscle M-line. Myofilament lattice assembly begins with positional cues laid down in the basement membrane and muscle cell membrane. UNC-89 responds to these signals, localizes, and then participates in assembling an M-line. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Phosphorylation Sites |
dbPAF PTMs: 110 (View all)
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Sequence (Fasta) | MASRRQKQFD RKYSSYRKFT ATEDVNYSTH SSRSSYRSES LTSRTDGRGR STSSEIIAGS 60 ESRSYPVYIA IQDYTPDKED VEAIPLEQGQ IVEVLDKKNS VRWLVRTKAR PPRSGWVPGS 120 YFETPTEFYK QRRRTREIEN VSLSDEQAAL VKRDQVYHEL LRSEEEFVSS LRTCVDDYIK 180 VLDDPEVPEA VKKNREELTL NIPELYNFHA NVMLKGLNYY SDDPGKVGQT FVRLEKDFES 240 HVEFYKQYAD TLKLLEEPEI KRFFEGLSAK NDAGASSFVD HVKEIADRMV QYQNYFKEFV 300 KYSARAHGSS KSIQKALELV TTIPQRVHDL EFTNNLKQHP GDTGKLGRII RHDAFQVWEG 360 DEPPKLRYVF LFRNKIMFTE QDASTSPPSY THYSSIRLDK YNIRQHTTDE DTIVLQPQEP 420 GLPSFRIKPK DFETSEYVRK AWLRDIAEEQ EKYAAERDAI SMTATSEMTA SSVDFDMNAS 480 DQQSEFSEWS GSRKSSLFPG PEEGGPPRKK VKSPPVISPT GSSTSIYSGG SSSIDWTTTG 540 TTLEMQGTRV TRTQYGFRTL QESSAKMCLK VTGYPLPDIT WYKDDVQLHE DERHTFYSDE 600 DGFFAMTIDP VQVTDTGRYT CMATNEYGQA STSAFFRVLK VEKEAAPPAF VTKLRDKECK 660 EGDVIDFECE VEGWPEPELV WLVDDQPLRP SHDFRLQYDG QTAKLEIRDA QPDDTGVYTV 720 KIQNEFGSIE SKAELFVQAD PDKNHVAPEF QATIEYVECD EGEEVRFKSV ITGDPNPEII 780 WFINGKPLSE SEKVKFISED GICILTIKDV TRHFDGMVTC QGSNRLGSAS CDGRLKVRVP 840 PAPPTFNKPL EDKTVQEKST VVFEVDVSGW PEPTLTFTLC GKELKNGEEG VEIVGHDGFY 900 RISIPNTSMD KHDGEIVAKA QNEHGTAESR ARLTVEQEEE ESRSAPTFLK DIEDQTVKTG 960 EFAVFETTVR GNPNPEVTWF INGHKMDQGS PGVKIEAHNH DHKLTIDSAQ YAGTVLCRAE 1020 NAVGRFETKA RLVVLAPEKQ KKPPKFVEIL VDKTETVDNT VVFEVRVEGE PKPTVTWYLK 1080 GEELKQSDRV EIREFDGSIK ISIKNIKIED AGEIRAVATN SEGSDETKAK LTVQKKPFAP 1140 EFDLRPVSLT VEKGSEAVFS AHAFGIPLPT YEWSVNGRKV RDGQEGARVT RDESTVDGAS 1200 ILTIDTATYY SEVNHLTISV VAENTLGAEE TGAQLTIEPK KESVVVEKQD LSSSEVQKEI 1260 AQQVKEASPE ATTTITMETS LTSTKTTTMS TTEVTSTVGG VTVETKESES ESATTVIGGG 1320 SGGVTEGSIS VSKIEVVSKT DSQTDVREGT PKRRVSFAEE ELPKEVIDSD RKKKKSPSPD 1380 KKEKSPEKTE EKPASPTKKT GEEVKSPKEK SPASPTKKEK SPAAEEVKSP TKKEKSPSSP 1440 TKKEKSPSSP TKKTGDEVKE KSPPKSPTKK EKSPEKPEDV KSPVKKEKSP DATNIVEVSS 1500 ETTIEKTETT MTTEMTHESE ESRTSVKKEK TPEKVDEKPK SPTKKDKSPE KSITEEIKSP 1560 VKKEKSPEKV EEKPASPTKK EKSPEKPASP TKKSENEVKS PTKKEKSPEK SVVEELKSPK 1620 EKSPEKADDK PKSPTKKEKS PEKSATEDVK SPTKKEKSPE KVEEKPTSPT KKESSPTKKT 1680 DDEVKSPTKK EKSPQTVEEK PASPTKKEKS PEKSVVEEVK SPKEKSPEKA EEKPKSPTKK 1740 EKSPEKSAAE EVKSPTKKEK SPEKSAEEKP KSPTKKESSP VKMADDEVKS PTKKEKSPEK 1800 VEEKPASPTK KEKTPEKSAA EELKSPTKKE KSPSSPTKKT GDESKEKSPE KPEEKPKSPT 1860 PKKSPPGSPK KKKSKSPEAE KPPAPKLTRD LKLQTVNKTD LAHFEVVVEH ATECKWFLDG 1920 KEITTAQGVT VSKDDQFEFR CSIDTTMFGS GTVSVVASNA AGSVETKTEL KVLETPKETK 1980 KPEFTDKLRD MEVTKGDTVQ MDVIALHSPL YKWYQNGNLL EDGKNGVTIK NEENKSSLII 2040 PNAQDSGKIT VEASNEVGSS ESSAQLTVNP PSTTPIVVDG PKSVTIKETE TAEFKATISG 2100 FPAPTVKWTI NEKIVEESRT ITTIKTEDVY TLKISNAKIE QTGTVKVTAQ NSAGQDSKQA 2160 DLKVEPNVKA PKFKSQLTDK VADEGEPLRW NLELDGPSPG TEVSWLLNGQ PLTKSDTVQV 2220 VDHGDGTYHV TIAEAKPEMS GTLTAKAKNA AGECETSAKV TVNGGNKKPE FVQAPQNHET 2280 TLEESVKFSA IVTGKPMPNV TWYLNNKKLI QSEEVKVKYV HETGKTSIRI QKPLMEHNGT 2340 IRVEAENVSG KVQATAQLKV DKKTEVPKFT TNMDDRQVKE GEDVKFTANV EGYPEPSVAW 2400 TLNGEPVSKH PNITVTDKDG EHTIEISAVT PEQAGELSCE ATNPVGSKKR DVQLAVKKVG 2460 DAPTFAKNLE DRLITEGELT LMDAKLNIVK PKPKITWLKD GVEITSDGHY KIVEEEDGSL 2520 KLSILQTKLE DKGRITIKAE SEFGVAECSA SLGVVKGRPM AKPAFQSDIA PINLTEGDTL 2580 ECKLLITGDP TPFVKWYIGT QLVCATEDTE ISNANGVYTM KIHGVTADMT GKIKCVAYNK 2640 AGEVSTEGPL KVVAPIPVEF ETSLCDATCR EGDTLKLRAV LLGEPEPVVS WYVNGKKLEE 2700 SQNIKIHSEK GTYTVTIKDI TCDYSGQVVC EAINEYGKAT SEATLLVLPR GEPPDFLEWL 2760 SNVRARTGTK VVHKVVFTGD PKPSLTWYIN NKEILNSDLY TIVTDDKTST LTINSFNPDV 2820 HVGEIICKAE NDAGEVSCTA NMITYTSDMF SESESEAQAE EFVGDDLTED ESLREEMHRT 2880 PTPVMAPKFI TKIKDTKAKK GHSAVFECVV PDTKGVCCKW LKDGKEIELI ARIRVQTRTG 2940 PEGHITQELV LDNVTPEDAG KYTCIVENTA GKDTCEATLT VIESLEKKSE KKAPEFIVAL 3000 QDKTTKTSEK VVLECKVIGE PKPKVSWLHD NKTITQESIT VESVEGVERV TITSSELSHQ 3060 GKYTCIAENT EGTSKTEAFL TVQGEAPVFT KELQNKELSI GEKLVLSCSV KGSPQPHVDF 3120 YSFSETTKVE TKITSSSRIA IEHDQTNTHW RMVISQITKE DIVSYKAIAT NSIGTATSTS 3180 KITTKVEAPV FEQGLKKTSV KEKEEIKMEV KVGGSAPDVE WFKDDKPVSE DGNHEMKKNP 3240 ETGVFTLVVK QAATTDAGKY TAKASNPAGT AESSAEAEVT QSLEKPTFVR ELVTTEVKIN 3300 ETATLSVTVK GVPDPSVEWL KDGQPVQTDS SHVIAKVEGS GSYSITIKDA RLEDSGKYAC 3360 RATNPAGEAK TEANFAVVKN LVPPEFVEKL SPLEVKEKES TTLSVKVVGT PEPSVEWFKD 3420 DTPISIDNVH VIQKQTAVGS FSLTINDARQ GDVGIYSCRA RNEAGEALTT ANFGIIRDSI 3480 PPEFTQKLRP LEVREQETLD LKVTVIGTPV PNVEWFKDDK PINIDNSHIF AKDEGSGHHT 3540 LTIKQARGED VGVYTCKATN EAGEAKTTAN MAVQEEIEAP LFVQGLKPYE VEQGKPAELV 3600 VRVEGKPEPE VKWFKDGVPI AIDNQHVIEK KGENGSHTLV IKDTNNADFG KYTCQATNKA 3660 GKDETVGELK IPKYSFEKQT AEEVKPLFIE PLKETFAVEG DTVVLECKVN KESHPQIKFF 3720 KNDQPVEIGQ HMQLEVLEDG NIKLTIQNAK KEDVGAYRCE AVNVAGKANT NADLKIQFAA 3780 KVEEHVTDES GQLEEIGQFE TVGDTASSKT DTGRGAPEFV ELLRSCTVTE KQQAILKCKV 3840 KGEPRPKIKW TKEGKEVEMS ARVRAEHKDD GTLTLTFDNV TQADAGEYRC EAENEYGSAW 3900 TEGPIIVTLE GAPKIDGEAP DFLQPVKPAV VTVGETAVLE GKISGKPKPS VKWYKNGEEL 3960 KPSDRVKIEN LDDGTQRLTV TNAKLDDMDE YRCEASNEFG DVWSDVTLTV KEPAQVAPGF 4020 FKELSAIQVK ETETAKFECK VSGTKPDVKW FKDGTPLKED KRVHFESTDD GTQRLVIEDS 4080 KTDDQGNYRI EVSNDAGVAN SKVPLTVVPS ETLKIKKGLT DVNVTQGTKI LLSVEVEGKP 4140 KTVKWYKGTE TVTSSQTTKI VQVTESEYKL EIESAEMSDT GAYRVVLSTD SFSVESSATV 4200 TVTKAAEKIS LPSFKKGLAD QSVPKGTPLV LEVEIEGKPK DVKWYKNGDE IKDGKVEDLG 4260 NGKYRLTIPD FQEKDVGEYS VTAANEAGEI ESKAKVNVSA KPEIVSGLVP TTVKQGETAT 4320 FNVKVKGPVK GVKWYKNGKE IPDAKTKDNG DGSYSLEIPN AQVEDAADYK VVVSNDAGDA 4380 DSSAALTVKL ADDGKDKVKP EIVSGLIPTT VKQGETATFN VKVKGPVKQV KWYKNGKEIP 4440 NAKAKDNGDG SYSLEIPNAQ LDDTADYKVV VSNDAGDADS SAALTVKLPG IAIVKGLEDA 4500 EVPKGKKAVL QVETNKKPKE IKWYKNGKEI TPSDKAQPGS DGDNKPQLVI PDAGDDDAAE 4560 YKVVLTDEDG NTADSSCALT VKLPAKEPKI IKGLEDQVVS IGSPIKLEIE TSGSPKTVKW 4620 YKNGKELPGA AAKTIKIQKI DDNKYVLEIP SSVVEDTGDY KVEVANEAGS ANSSGKITVE 4680 PKITFLKPLK DQSITEGENA EFSVETNTKP RIVKWYKNGQ EIKPNSRFII EQKTDTKYQL 4740 VIKNAVRDDA DTYKIVLENT AGEAESSAQL TVKKAKAGLC KIVKGLEDQV VAKGAKMVFE 4800 VKIQGEPEDV RWLRDANVIS AGANAIIEKI DDTTYRLIIP SADLKDAGEY TVEVINESGK 4860 AKSDAKGEVD EKPEIVRGLE NIEIPEGDDD VFKVEVSAPV RQVKWYKNDQ EIKPNSHLEA 4920 KKIGPKKYEL AINRAQLDDG ADYKVVLSNA AGDCDSSAAL TVVKPNVLKI VDGLKDVDVE 4980 EPQPVELKVK VEGIPKVIKW YKNGQELKPD ADGFKFEEKP ESGEFSLTIP SSKKSDGGAY 5040 RVVLGNDKGE VYSGSVVHVK SAKSSEPTSG ANFLSPLKDT EVEEGDMLTL QCTIAGEPFP 5100 EVIWEKDGVV LQKDDRITMR VALDGTATLR IRSAKKSDIG QYRVTAKNEA GSATSDCKVT 5160 VTEQGEQPSK PKFVIPLKTG AALPGDKKEF NVKVRGLPKP TLQWFLNGIP IKFDDRITLD 5220 DMADGNYCLT IRDVREEDFG TLKCIAKNEN GTDETVCEFQ QGAGHDDGSR DDLRYPPRFN 5280 VPLWDRRIPV GDPMFIECHV DANPTAEVEW FKDGKKIEHT AHTEIRNTVD GACRIKIIPF 5340 EESDIGVYMC VAVNELGQAE TQATYQVEIL EHVEEEKRRE YAPKINPPLE DKTVNGGQPI 5400 RLSCKVDAIP RASVVWYKDG LPLRADSRTS IQYEEDGTAT LAINDSTEED IGAYRCVATN 5460 AHGTINTSCS VNVKVPKQEV KKEGEEPFFT KGLVDLWADR GDSFTLKCAV TGDPFPEIKW 5520 YRNGQLLRNG PRTVIETSPD GSCSLTVNES TMSDEGIYRC EAENAHGKAK TQATAHVQMA 5580 LGKTEKPKMD EGKPPKFILE LSDMSVSLGN VIDLECKVTG LPNPSVKWSK DGGPLIEDSR 5640 FEWSNEASKG VYQLRIKNAT VHDEGTYRCV ATNENGSATT KSFVRMDDGL GSGVVTASQP 5700 PRFTLKMGDV RTTEGQPLKL ECKVDASPLP EMVWYKDGAI VTPSDRIQIS LSPDGVATLL 5760 IPSCVYDDDG IYRVIATNPS GTAQDKGTAT VKKLPRDSGA RRSADRDVFD ANKAPKLMEP 5820 LENIRIPEKQ SFRLRCKFSG DPKPTIKWFK DGERVFPYGR LQLIESPDGV CELVVDSATR 5880 QDAGGYRCVA ENTYGSARTS CDVNVIRGDR KPRDIDSSIR EGKAPGFTTP LTIRRAKPGD 5940 SVTFECLPFG NPFPSIKWLK DGLELFSDEK IKMEAAADGT QRLILSDVTF LSEGYFRCVA 6000 TNEHGTASTK AELVIEGDRT IGSRPLPEVN GEPEECKPRI RRGLYNMSIH EGNVVEMIVC 6060 ATGIPTPTVK WYKDGQEIVG DGPDGKRVIF TDERGIHHLV IVNASPDDEG EYSLEATNKL 6120 GSAKTEGSLN IIRPRHIADA DERGGMPFPP GFVRQLKNKH VFNHMPTIFD CLVVGHPAPE 6180 VEWFHNGKKI VPGGRIKIQS CGGGSHALII LDTTLEDAGE YVATAKNSHG SASSSAVLDV 6240 TVPFLDSIKF NGEIDVTPYL TEEYGFKKLN TASLPTPPDR GPFIKEVTGH YLTLSWIPTK 6300 RAPPRYPQVT YVIEIRELPE KQWSLLEYNI PEPVCKVRNL ELGKSYQFRV RAENIYGISD 6360 PSPASPPSRL MAPPQPVFDR RTNKVIPLLD PYAEKALDMR YSEQYACAPW FSPGVVEKRY 6420 CAENDTLTIV LNVSGFPDPD IKWKFRGWDI DTSSPTSKCK VYTYGGSETT LAITGFSKEN 6480 VGQYQCFAKN DYGDAQQNIM VDLATRPNFI QPLVNKTFSS AQPMRMDVRV DGEPFPELKW 6540 MKEWRPIVES SRIKFVQDGP YLCSLIINDP MWRDSGIYSC VAVNDAGQAT TSCTVTVEAE 6600 GDYNDVELPR RRVTIESRRV RELYEISEKD EKLAAEGAPF RVKEKATGRE FLAQLRPIDD 6660 ALMRHVDIHN SLDHPGIVQM HRVLRDEKLA LVVFDNANST IDGLSSLAHP GVEIAEPKGV 6720 NRETCVRVFV RQLLLALKHM HDLRIAHLDL RPETILLQDD KLKLADFGQA RRLLRGLITG 6780 EIKGSPEFVS PEIVRSYPLT LATDMWSTGV LTYVLLTGLS PFHGDNDNET LANVDSCQFD 6840 SSPLGNFSYD AGDFVKKLLT EIPVSRLTVD EALDHPWIND EKLKTEPLSA DTLREFKYQH 6900 KWLERRVFVQ QTPSEQILEA ILGPATAQAQ QNAPVAPEGR RPAEIYDYLR IQPKKPPPTV 6960 EYVPQPRKEH PPFIDEFGQL IDGDAFDRPE GTGFEGPHRQ PPQIPPQPQR PNQAAHDSRR 7020 HEQQPQHQGQ PQRIPVDQYG RPLVDPRYLN DPSHRPSSLD DAPFYVDKYG NPVHFDKYGR 7080 PMAPQNLEKR KLIPQDKGET PSHSKKEKTQ HPVATPILAS PGGDQQQQKI PMRMIRGERR 7140 EIEEEIANRI LSDISEEGSI AGSLASLEDF EIPKDFQVEA SEPSTPTLTP EVTIRETIPK 7200 PTPSPTSPQK SPVPQPQGLL IPAKVTYSDS ILAGLPAADK KVLEDAENDP SIPVGAPLFL 7260 EGLHGSDLTI DTTSASGLIK VTSPAINLSP NPKSPRRSTP GTKSPVVLSP RQEHSMEVLI 7320 ATKRGKPGFL PPGELAEDID DEDAFMDDRK KQVKPKDHDG ENDFKDEKER LEKDKNRRTV 7380 NLDDLDKYRP SAFYKDDSDF GHPGYDIDAT PWDSHYQIGP DTYLMAARGA AFNSRVRNYR 7440 EELFGMGAPT VKQGFLGVRN RDITVRERRR YTDILRETTQ GLEPKSHEQS TALLQKAPSA 7500 TAIERIKADI EKVTPCATKK NDDGTFAPIF TARLRDVYLR KNQPAIFECA VSASPAPKVT 7560 WDFQGKILES NDRVTIEQDN NVARLILNHA APYDLGEYVC TAINEYGTDK SSCRLISGET 7620 PSRPGRPEAE LSSDTEIFIQ WEAPEGPTYL EGITYRLEYR VAGPNDHGDP WITVSEKIDD 7680 ESVIVKHLSP LGIYQFRVTA QNGFGLGLPS LSSRIVQTHG KGAPKLQIDV LKSEIRLNVV 7740 SMPQKSTNQL GGISEESEED SEARTANEDM KSNLQLQTDD PTGRFQIGGL KFKGRFSVIR 7800 DAVDSTTEGH AHCAVKIRHP SSEAISEYES LRDGQHENVQ RLIAAFNNSN FLYLLSERLY 7860 EDVFSRFVFN DYYTEEQVAL TMRQVTSALH FLHFKGIAHL DVNPHNIMFQ SKRSWVVKLV 7920 DFGRAQKVSG AVKPVDFDTK WASPEFHIPE TPVTVQSDMW GMGVVTFCLL AGFHPFTSEY 7980 DREEEIKENV INVKCDPNLI PVNASQECLS FATWALKKSP VRRMRTDEAL SHKFLSSDPS 8040 MVRRRESIKY SASRLRKLAA MIRQPTFSQP ISEELESKYG K 8082 |
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Keyword | KW-0002--3D-structure |
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Interpro | IPR000219--DH-domain |
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PROSITE | PS50010--DH_2 |
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Pfam | PF00041--fn3 |
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Gene Ontology | GO:0031672--C:A band |