dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000193
Uniprot Accession O01737; O01737_CAEEL; D5LYH1;
Genbank Protein ID NP_498455.2;
Genbank Nucleotide ID NM_066054.4;
Protein Name Notch signaling pathway homolog-1
Protein Synonyms/Alias
Gene Name let-765
Gene Synonyms/Alias nsh-1;CELE_F20H11.2;F20H11.2;
Organism Caenorhabditis elegans
NCBI Taxa ID 6239
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
139TAPTVNQSEPSTPTVPhosphoPep 2.019060867
570ASPRLQTTPQPLTKSPhospho.ELM 9.0;PHOSIDA;curated19530675; 21081558; 18806794
Sequence
(Fasta)
MDDILSAALA ESGLDFLCQQ SSPTPSTSGS IHDDAGQSFS NNTHTPSVSQ FFDETSNDSH 60
SSSAYYTPMA TPFVSTEDGG VPTSFFGMDE EDGGCTIMTT AGTSGSNNID GIEDAGGGMY 120
YPHVKVIPRK HTAPTVNQSE PSTPTVTIVP KKEDPLFETN TADSPTPSGD TSTTASYEGN 180
DGLEDQETTS DRQNPMFVQT ARSTDGRLDT PSTSATVSPH ITSSLTQRSH TSSPASSASE 240
GTVVPPRKKG LPITTGSIVK RTVQTKDGLQ TQYLKAFVNE NGEKIYKLLS PVAASAVARG 300
TLPPGMGRGG STIGRGGTMV NKNGERLMVV KNHVGPNGQM LVKRMVSPAG TRIVANGGQG 360
RGQPIYRAVD GSNGPTHLLR RTTTTGQPTR GAPVGMAARH AVRGGTVYGG GNGYRVNLVG 420
RGTGGSTMVH HQPLNRISSQ RSVAPVGRVL NRGALRNGAQ QPLHVSTSSP AFHYMEEQPS 480
PTTNGMVIQA KTPGAGVIQA RHMQSQQSFP SGGPARVLMN RSSTNAGLSR MVGGGYDQQL 540
PTAPNGRLMI PSTAVRVPGS GMASPRLQTT PQPLTKSQKA KDEMKMAYQV GREEALQQRR 600
NDLEDDEENL GYAETYSEYT PAKLRSGMAH PDSVVESASL SSVSPPDVKY QISIPEYLID 660
MGHISALQLE AVIYACQMHE RRMPSGERYG YLIGDGAGVG KGRTVACIIF ENYLQGRKRA 720
IWLSVSSDLK FDAERDLRDC GAPNIPVYAL NKMKYAKISG KENGSIKKGV MFATYTSLIG 780
ECRGAKSRKY RSRISQLIQW FGQDYDGVII LDECHRAKNL VPTAGAKPTK TGRMVLELQK 840
ALPNARVVYA SATGATEPRN MAYMTRLGLW GERQAFPEFH DFISAVERRG VGAMEIVAMD 900
MKQRGLYLAR QLSFRGVSFA VQEVQLSSEF VKMYDAAVKL WMEARRQFQT VIETMDEEER 960
STCKTVWGQF WACHQRFFKY LCIAAKVDTC VQLSREAIKA KKCVVIGLQS TGESATLETL 1020
EEMGGELNEF VSTAKTVLYG LIDKHFPTDA SFSMGDRDIF KDFDDFERPA KRRKTRETLS 1080
FLGDVGFDTW TGVTTGMGGR VGDGVTKNIT RGLSGIGRSS MSSSTGNTNN EDANSTTSES 1140
SDGSDDEVEN DMISENGGES GDLESAREEA EGARTLEDGE QDEWVKALLA EAESSSDDSD 1200
EEVVKDEDED EEAESKSGET HEQEEEFNPF MCDFTNDDPW AHNQQIVEDT PQKDRKAKKR 1260
KRDEEEAERL REKVRKREER REKKRRRAIR RAEREKQRRN EELQARGSAT DFITSSRICG 1320
NGSGEQDDIN PMLIKTELLA AVERLAPSLP ANTLDQLIDE MGGPEYVAEM TGRRGHMVTS 1380
ETGDVMYQRR NANAEVSLEL INMEEKEKFM RGEKLIAIIS EAASSGISLQ SDRRAINKRR 1440
RVHITLELPW SADKAIQQFG RTHRSNQVSG PEYVFLISEL AGEKRFASIV AKRLESLGAL 1500
THGDRRATET RDLSQFNMDN KYGRVALDTL LKTVIGQAGT PLIDPPKDYK AGEFFEDMRL 1560
YMEGVGLLAK NKTGQYTIEK EAATIPKFLN RILGLPVHAQ NSLFHYFSEI VAELIAQSKH 1620
DGTYDTGIMD LGTGDDQVRK LETRVFTGRV DNGSFRVEIH KIGVERGVSW EEAMELHKEH 1680
SNDDDGFYIC HPGGANTANT KKVAALVYGI GKIRMDNGAR LYAITRPSTG RSPKLMTMAD 1740
LSKRFHKVSI DEAKEVWKQQ YDSAANMCQH NYVYGKCRTE SNGTYCEVGR RTRTYFVLSG 1800
SVLSVWPIVE EVLAGSDRKS SRMQVIRVRT EQDQKIVGLL VLPTHVRHLV QQLETHCGRS 1860
YVKTEP 1867
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR027417--P-loop_NTPase
IPR026937--SBNO_Helicase_C_dom
IPR026741--SNO

PROSITE
Pfam

PF13871--Helicase_C_4

Gene Ontology

GO:0005634--C:nucleus
GO:0045138--P:nematode male tail tip morphogenesis
GO:0042660--P:positive regulation of cell fate specification
GO:0046579--P:positive regulation of Ras protein signal transduction
GO:0006355--P:regulation of transcription, DNA-templated
GO:0072327--P:vulval cell fate specification