| Tag |
Content |
| dbPAF ID |
dbPAF-0000170 |
| Uniprot Accession |
O01479; TMOD_CAEEL; Q95Q88;
|
| Genbank Protein ID |
NP_491734.1; NP_491735.1;
|
| Genbank Nucleotide ID |
NM_059333.3; NM_059334.3;
|
| Protein Name |
Tropomodulin |
| Protein Synonyms/Alias |
Tmod-like protein;cTmd1;Uncoordinated protein 94; |
| Gene Name |
unc-94 |
| Gene Synonyms/Alias |
tmd-1;C06A5.7; |
| Organism |
Caenorhabditis elegans |
| NCBI Taxa ID |
6239 |
Functional Description
(View all) |
Acts as the pointed end capping protein which maintains the length and dynamics of the actin filament. Blocks the elongation and depolymerization of the actin filaments at the pointed end (By similarity).Functional Description
Acts as the pointed end capping protein which maintains the length and dynamics of the actin filament. Blocks the elongation and depolymerization of the actin filaments at the pointed end (By similarity). |
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 208 | TFNGIMQSYVPRIVP | curated | 18806794 |
|
Sequence
(Fasta) | MSQAKTDYYS EEKTFSAPSA NSQQGTQLPS KVYNKGLKDL EDNDIEGLLS SLSIDELEDL 60
NNDFDPDNSM LPPSQRCRDQ TDKEPTGPYK RDNLLKFLED KAKTEKDWED VCPYTPGQKR 120
GKVYDSDSGR NSEEPENGKM EMPIEIDLDD DEEELECALV TAPEKDLVDL AGILGMHNVL 180
NQPQYYNALK GKTQDESTGT TFNGIMQSYV PRIVPDEPDN DTDVESCINR LREDDTDLKE 240
VNINNMKRVS KERIRSLIEA ACNSKHIEKF SLANTAISDS EARGLIELIE TSPSLRVLNV 300
ESNFLTPELL ARLLRSTLVT QSIVEFKADN QRQSVLGNQV EMDMMMAIEE NESLLRVGIS 360
FASMEARHRV SEALERNYER VRLRRLGKDP NV
393Fasta Sequence
>O01479|unc-94|Caenorhabditis elegans
MSQAKTDYYSEEKTFSAPSANSQQGTQLPSKVYNKGLKDLEDNDIEGLLSSLSIDELEDLNNDFDPDNSMLPPSQRCRDQTDKEPTGPYKRDNLLKFLEDKAKTEKDWEDVCPYTPGQKRGKVYDSDSGRNSEEPENGKMEMPIEIDLDDDEEELECALVTAPEKDLVDLAGILGMHNVLNQPQYYNALKGKTQDESTGTTFNGIMQSYVPRIVPDEPDNDTDVESCINRLREDDTDLKEVNINNMKRVSKERIRSLIEAACNSKHIEKFSLANTAISDSEARGLIELIETSPSLRVLNVESNFLTPELLARLLRSTLVTQSIVEFKADNQRQSVLGNQVEMDMMMAIEENESLLRVGISFASMEARHRVSEALERNYERVRLRRLGKDPNV
|
| Keyword |
KW-0002--3D-structure
KW-0009--Actin-binding
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-1185--Reference proteome
|
| Interpro |
IPR004934--TMOD
IPR030137--TMOD_invertebrate
|
| PROSITE |
|
| Pfam |
PF03250--Tropomodulin
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0030016--C:myofibril
GO:0005865--C:striated muscle thin filament
GO:1990357--C:terminal web
GO:0051015--F:actin filament binding
GO:0005523--F:tropomyosin binding
GO:0009792--P:embryo development ending in birth or egg hatching
GO:0040011--P:locomotion
GO:0071689--P:muscle thin filament assembly
GO:0030239--P:myofibril assembly
GO:0030835--P:negative regulation of actin filament depolymerization
GO:0002119--P:nematode larval development
GO:0051694--P:pointed-end actin filament capping
GO:0045214--P:sarcomere organization
|
