| Tag |
Content |
| dbPAF ID |
dbPAF-0000157 |
| Uniprot Accession |
O00755; WNT7A_HUMAN; Q96H90; Q9Y560;
|
| Genbank Protein ID |
NP_004616.2;
|
| Genbank Nucleotide ID |
NM_004625.3;
|
| Protein Name |
Protein Wnt-7a |
| Protein Synonyms/Alias |
|
| Gene Name |
WNT7A |
| Gene Synonyms/Alias |
|
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts (By similarity).Functional Description
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts (By similarity). |
Phosphorylation Sites
|
dbPAF PTMs: 4 |
Sequence
(Fasta) | MNRKARRCLG HLFLSLGMVY LRIGGFSSVV ALGASIICNK IPGLAPRQRA ICQSRPDAII 60
VIGEGSQMGL DECQFQFRNG RWNCSALGER TVFGKELKVG SREAAFTYAI IAAGVAHAIT 120
AACTQGNLSD CGCDKEKQGQ YHRDEGWKWG GCSADIRYGI GFAKVFVDAR EIKQNARTLM 180
NLHNNEAGRK ILEENMKLEC KCHGVSGSCT TKTCWTTLPQ FRELGYVLKD KYNEAVHVEP 240
VRASRNKRPT FLKIKKPLSY RKPMDTDLVY IEKSPNYCEE DPVTGSVGTQ GRACNKTAPQ 300
ASGCDLMCCG RGYNTHQYAR VWQCNCKFHW CCYVKCNTCS ERTEMYTCK
Fasta Sequence
>O00755|WNT7A|Homo sapiens(Human)
MNRKARRCLGHLFLSLGMVYLRIGGFSSVVALGASIICNKIPGLAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQNARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK
|
| Keyword |
KW-0002--3D-structure
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0225--Disease mutation
KW-1015--Disulfide bond
KW-0272--Extracellular matrix
KW-0325--Glycoprotein
KW-0449--Lipoprotein
KW-1185--Reference proteome
KW-0964--Secreted
KW-0732--Signal
KW-0879--Wnt signaling pathway
|
| Interpro |
IPR005817--Wnt
IPR013300--Wnt7
IPR018161--Wnt_CS
|
| PROSITE |
PS00246--WNT1
|
| Pfam |
PF00110--wnt
|
| Gene Ontology |
GO:0009986--C:cell surface
GO:0030666--C:endocytic vesicle membrane
GO:0005788--C:endoplasmic reticulum lumen
GO:0070062--C:extracellular exosome
GO:0005576--C:extracellular region
GO:0005615--C:extracellular space
GO:0005796--C:Golgi lumen
GO:0005886--C:plasma membrane
GO:0005578--C:proteinaceous extracellular matrix
GO:0005125--F:cytokine activity
GO:0005109--F:frizzled binding
GO:0048018--F:receptor agonist activity
GO:0005102--F:receptor binding
GO:0001525--P:angiogenesis
GO:0008105--P:asymmetric protein localization
GO:0060070--P:canonical Wnt signaling pathway
GO:0001502--P:cartilage condensation
GO:0045165--P:cell fate commitment
GO:0021846--P:cell proliferation in forebrain
GO:0071560--P:cellular response to transforming growth factor beta stimulus
GO:0022009--P:central nervous system vasculogenesis
GO:0021707--P:cerebellar granule cell differentiation
GO:0002062--P:chondrocyte differentiation
GO:0009953--P:dorsal/ventral pattern formation
GO:0000578--P:embryonic axis specification
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0035116--P:embryonic hindlimb morphogenesis
GO:0030010--P:establishment of cell polarity
GO:0070307--P:lens fiber cell development
GO:0043066--P:negative regulation of apoptotic process
GO:0050768--P:negative regulation of neurogenesis
GO:0030182--P:neuron differentiation
GO:0007269--P:neurotransmitter secretion
GO:0035567--P:non-canonical Wnt signaling pathway
GO:0060066--P:oviduct development
GO:0060021--P:palate development
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0010595--P:positive regulation of endothelial cell migration
GO:0060054--P:positive regulation of epithelial cell proliferation involved in wound healing
GO:0046330--P:positive regulation of JNK cascade
GO:0051965--P:positive regulation of synapse assembly
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0031133--P:regulation of axon diameter
GO:0032355--P:response to estradiol
GO:0007548--P:sex differentiation
GO:0014719--P:skeletal muscle satellite cell activation
GO:0014834--P:skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
GO:0048103--P:somatic stem cell division
GO:0035019--P:somatic stem cell population maintenance
GO:0048864--P:stem cell development
GO:0050808--P:synapse organization
GO:0061038--P:uterus morphogenesis
GO:0035659--P:Wnt signaling pathway involved in wound healing, spreading of epidermal cells
|
