dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000147
Uniprot Accession O00634; NET3_HUMAN;
Genbank Protein ID NP_006172.1;
Genbank Nucleotide ID NM_006181.2;
Protein Name Netrin-3
Protein Synonyms/Alias Netrin-2-like protein;
Gene Name NTN3
Gene Synonyms/Alias NTN2L;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Netrins control guidance of CNS commissural axons and peripheral motor axons.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
56LGREVLASSTCGRPAPhosphoSitePlus22135298
58REVLASSTCGRPATRPhosphoSitePlus22135298
64STCGRPATRACDASDPhosphoSitePlus22135298
Sequence
(Fasta)
MPGWPWGLLL TAGTLFAALS PGPPAPADPC HDEGGAPRGC VPGLVNAALG REVLASSTCG 60
RPATRACDAS DPRRAHSPAL LTSPGGTASP LCWRSESLPR APLNVTLTVP LGKAFELVFV 120
SLRFCSAPPA SVALLKSQDH GRSWAPLGFF SSHCDLDYGR LPAPANGPAG PGPEALCFPA 180
PLAQPDGSGL LAFSMQDSSP PGLDLDSSPV LQDWVTATDV RVVLTRPSTA GDPRDMEAVV 240
PYSYAATDLQ VGGRCKCNGH ASRCLLDTQG HLICDCRHGT EGPDCGRCKP FYCDRPWQRA 300
TARESHACLA CSCNGHARRC RFNMELYRLS GRRSGGVCLN CRHNTAGRHC HYCREGFYRD 360
PGRALSDRRA CRACDCHPVG AAGKTCNQTT GQCPCKDGVT GLTCNRCAPG FQQSRSPVAP 420
CVKTPIPGPT EDSSPVQPQD CDSHCKPARG SYRISLKKFC KKDYAVQVAV GARGEARGAW 480
TRFPVAVLAV FRSGEERARR GSSALWVPAG DAACGCPRLL PGRRYLLLGG GPGAAAGGAG 540
GRGPGLIAAR GSLVLPWRDA WTRRLRRLQR RERRGRCSAA 581
Keyword

KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0272--Extracellular matrix
KW-0325--Glycoprotein
KW-0424--Laminin EGF-like domain
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0964--Secreted
KW-0732--Signal

Interpro

IPR002049--Laminin_EGF
IPR008211--Laminin_N
IPR001134--Netrin_domain
IPR018933--Netrin_module_non-TIMP
IPR008993--TIMP-like_OB-fold

PROSITE

PS00022--EGF_1
PS01248--EGF_LAM_1
PS50027--EGF_LAM_2
PS51117--LAMININ_NTER
PS50189--NTR

Pfam

PF00053--Laminin_EGF
PF00055--Laminin_N
PF01759--NTR

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0005578--C:proteinaceous extracellular matrix
GO:0007411--P:axon guidance
GO:0042692--P:muscle cell differentiation
GO:0051149--P:positive regulation of muscle cell differentiation