dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0000143 |
| Uniprot Accession | O00625; PIR_HUMAN; Q5U0G0; Q6FHD2; |
| Genbank Protein ID | NP_001018119.1; NP_003653.1; |
| Genbank Nucleotide ID | NM_001018109.2; NM_003662.3; |
| Protein Name | Pirin |
| Protein Synonyms/Alias | Probable quercetin 2,3-dioxygenase PIR;Probable quercetinase; |
| Gene Name | PIR |
| Gene Synonyms/Alias | |
| Organism | Homo sapiens(Human) |
| NCBI Taxa ID | 9606 |
| Functional Description (View all) |
Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro). |
| Phosphorylation Sites |
dbPAF PTMs: 5 |
| Sequence (Fasta) | MGSSKKVTLS VLSREQSEGV GARVRRSIGR PELKNLDPFL LFDEFKGGRP GGFPDHPHRG 60 FETVSYLLEG GSMAHEDFCG HTGKMNPGDL QWMTAGRGIL HAEMPCSEEP AHGLQLWVNL 120 RSSEKMVEPQ YQELKSEEIP KPSKDGVTVA VISGEALGIK SKVYTRTPTL YLDFKLDPGA 180 KHSQPIPKGW TSFIYTISGD VYIGPDDAQQ KIEPHHTAVL GEGDSVQVEN KDPKRSHFVL 240 IAGEPLREPV IQHGPFVMNT NEEISQAILD FRNAKNGFER AKTWKSKIGN 291 |
| Keyword | KW-0002--3D-structure |
| Interpro | IPR012093--Pirin |
| PROSITE | |
| Pfam | |
| Gene Ontology | GO:0005737--C:cytoplasm |