dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000135
Uniprot Accession O00574; CXCR6_HUMAN; O00575; Q9HCA5;
Genbank Protein ID NP_006555.1; XP_005264866.1; XP_011531592.1; XP_011531593.1;
Genbank Nucleotide ID NM_006564.1; XM_005264809.2; XM_011533290.1; XM_011533291.1;
Protein Name C-X-C chemokine receptor type 6
Protein Synonyms/Alias
Gene Name CXCR6
Gene Synonyms/Alias BONZO;STRL33;TYMSTR;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
182LDKLICGYHDEAISTPhosphoSitePlus22135298
Sequence
(Fasta)		MAEHDYHEDY GFSSFNDSSQ EEHQDFLQFS KVFLPCMYLV VFVCGLVGNS LVLVISIFYH 60
KLQSLTDVFL VNLPLADLVF VCTLPFWAYA GIHEWVFGQV MCKSLLGIYT INFYTSMLIL 120
TCITVDRFIV VVKATKAYNQ QAKRMTWGKV TSLLIWVISL LVSLPQIIYG NVFNLDKLIC 180
GYHDEAISTV VLATQMTLGF FLPLLTMIVC YSVIIKTLLH AGGFQKHRSL KIIFLVMAVF 240
LLTQMPFNLM KFIRSTHWEY YAMTSFHYTI MVTEAIAYLR ACLNPVLYAF VSLKFRKNFW 300
KLVKDIGCLP YLGVSHQWKS SEDNSKTFSA SHNVEATSMF QL 343
Keyword

KW-1003--Cell membrane
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0297--G-protein coupled receptor
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0621--Polymorphism
KW-0675--Receptor
KW-1185--Reference proteome
KW-0807--Transducer
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR002235--Chemokine_CXCR6
IPR000355--Chemokine_rcpt
IPR000276--GPCR_Rhodpsn
IPR017452--GPCR_Rhodpsn_7TM
PROSITE

PS00237--G_PROTEIN_RECEP_F1_1
PS50262--G_PROTEIN_RECEP_F1_2
Pfam

PF00001--7tm_1
Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0005886--C:plasma membrane
GO:0016494--F:C-X-C chemokine receptor activity
GO:0015026--F:coreceptor activity
GO:0004930--F:G-protein coupled receptor activity
GO:0006935--P:chemotaxis
GO:0007186--P:G-protein coupled receptor signaling pathway
GO:0006954--P:inflammatory response
GO:0019079--P:viral genome replication