dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000128
Uniprot Accession O00559; RCAS1_HUMAN; A8K3N6; Q5Y8C7; Q6IB20; Q9BS76;
Genbank Protein ID NP_001265867.1; NP_004206.1; NP_936056.1;
Genbank Nucleotide ID NM_001278938.1; NM_004215.4; NM_198120.2;
Protein Name Receptor-binding cancer antigen expressed on SiSo cells
Protein Synonyms/Alias Cancer-associated surface antigen RCAS1;Estrogen receptor-binding fragment-associated gene 9 protein;
Gene Name EBAG9
Gene Synonyms/Alias RCAS1;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.
Phosphorylation Sites
 dbPAF PTMs: 14
PositionPeptidesSourceReferences ( PMIDs )
36SGRGRKLSGDQITLPdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated15144186; 17081983; 17487921; 18088087; 18187866; 18669648;
41KLSGDQITLPTTVDYdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoSitePlus;UniProt;curated15144186; 16381945; 23193290; 14729942; 15570572; 19651622;
48TLPTTVDYSSVPKQTdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus15144186; 16381945; 23193290; 14729942; 15570572; 18988627;
49LPTTVDYSSVPKQTDPhosphoSitePlus;curated22135298; 24667141
50PTTVDYSSVPKQTDVPhosphoSitePlus22135298
61QTDVEEWTSWDEDAPcurated25627689
62TDVEEWTSWDEDAPTPhosphoSitePlus;curated22135298; 25627689; 22199227
82GGNGNVATQQNSLEQPhosphoSitePlus22135298
86NVATQQNSLEQLEPDdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated19413330; 16381945; 23193290; 18988627; 22135298; 25627689;
94LEQLEPDYFKDMTPTdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;UniProt15592455; 16381945; 23193290; 18988627; 22135298
99PDYFKDMTPTIRKTQPhosphoSitePlus;curated22135298; 25627689
101YFKDMTPTIRKTQKIPhosphoSitePlus22135298
134FSSRLAATQDLPFIHPhosphoSitePlus22135298
213NKIGVKLS-------curated22199227
Sequence
(Fasta)		MAITQFRLFK FCTCLATVFS FLKRLICRSG RGRKLSGDQI TLPTTVDYSS VPKQTDVEEW 60
TSWDEDAPTS VKIEGGNGNV ATQQNSLEQL EPDYFKDMTP TIRKTQKIVI KKREPLNFGI 120
PDGSTGFSSR LAATQDLPFI HQSSELGDLD TWQENTNAWE EEEDAAWQAE EVLRQQKLAD 180
REKRAAEQQR KKMEKEAQRL MKKEQNKIGV KLS 214
Keyword

KW-0025--Alternative splicing
KW-0053--Apoptosis
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0735--Signal-anchor
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR017025--Cancer-assoc_antigen_RCAS1
PROSITE
Pfam
Gene Ontology

GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0030141--C:secretory granule
GO:0016505--F:peptidase activator activity involved in apoptotic process
GO:0001558--P:regulation of cell growth