dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000124
Uniprot Accession O00534; VMA5A_HUMAN; Q6UN19; Q6UN20; Q9BVF8;
Genbank Protein ID NP_001123614.1; NP_055437.2; NP_938057.1;
Genbank Nucleotide ID NM_001130142.1; NM_014622.4; NM_198315.2;
Protein Name von Willebrand factor A domain-containing protein 5A
Protein Synonyms/Alias Breast cancer suppressor candidate 1;BCSC-1;Loss of heterozygosity 11 chromosomal region 2 gene A protein;
Gene Name VWA5A
Gene Synonyms/Alias BCSC1;LOH11CR2A;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis.
Phosphorylation Sites
 dbPAF PTMs: 13
PositionPeptidesSourceReferences ( PMIDs )
9VHFCGLLTLHREPVPPhosphoSitePlus22135298
92TNYEKAISQGHQAFLPhosphoSitePlus22135298
104AFLLEGDSSSRDVFScurated25627689
105FLLEGDSSSRDVFSCcurated25627689
106LLEGDSSSRDVFSCNcurated25627689
202VQSNCPLSPTEYLGEPhosphoSitePlus;curated22135298; 25627689
204SNCPLSPTEYLGEDKPhosphoSitePlus22135298
289FIFLMDRSGSMQSPMPhosphoSitePlus22135298
291FLMDRSGSMQSPMSSPhosphoSitePlus22135298
381QNIYRGPSIPGHPLQPhosphoSitePlus22135298
639LHSDRPPSASQPRGEcurated25627689
660KTFQMDDYSLCGLISdbPTM 3.0;PhosphoSitePlus;curated18180459; 20736484; 16381945; 23193290; 22135298; 25627689;
661TFQMDDYSLCGLISHPhosphoSitePlus22135298
Sequence
(Fasta)		MVHFCGLLTL HREPVPLKSI SVSVNIYEFV AGVSATLNYE NEEKVPLEAF FVFPMDEDSA 60
VYSFEALVDG KKIVAELQDK MKARTNYEKA ISQGHQAFLL EGDSSSRDVF SCNVGNLQPG 120
SKAAVTLKYV QELPLEADGA LRFVLPAVLN PRYQFSGSSK DSCLNVKTPI VPVEDLPYTL 180
SMVATIDSQH GIEKVQSNCP LSPTEYLGED KTSAQVSLAA GHKFDRDVEL LIYYNEVHTP 240
SVVLEMGMPN MKPGHLMGDP SAMVSFYPNI PEDQPSNTCG EFIFLMDRSG SMQSPMSSQD 300
TSQLRIQAAK ETLILLLKSL PIGCYFNIYG FGSSYEACFP ESVKYTQQTM EEALGRVKLM 360
QADLGGTEIL APLQNIYRGP SIPGHPLQLF VFTDGEVTDT FSVIKEVRIN RQKHRCFSFG 420
IGEGTSTSLI KGIARASGGT SEFITGKDRM QSKALRTLKR SLQPVVEDVS LSWHLPPGLS 480
AKMLSPEQTV IFRGQRLISY AQLTGRMPAA ETTGEVCLKY TLQGKTFEDK VTFPLQPKPD 540
VNLTIHRLAA KSLLQTKDMG LRETPASDKK DALNLSLESG VISSFTAFIA INKELNKPVQ 600
GPLAHRDVPR PILLGASAPL KIKCQSGFRK ALHSDRPPSA SQPRGELMCY KAKTFQMDDY 660
SLCGLISHKD QHSPGFGENH LVQLIYHQNA NGSWDLNEDL AKILGMSLEE IMAAQPAELV 720
DSSGWATILA VIWLHSNGKD LKCEWELLER KAVAWMRAHA GSTMPSVVKA AITFLKSSVD 780
PAIFAF 787
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0043--Tumor suppressor
Interpro

IPR013694--VIT
IPR002035--VWF_A
PROSITE

PS51468--VIT
PS50234--VWFA
Pfam

PF08487--VIT
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus