dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000119
Uniprot Accession O00512; BCL9_HUMAN; Q5T489;
Genbank Protein ID NP_004317.2; XP_005273028.1; XP_006711546.1;
Genbank Nucleotide ID NM_004326.3; XM_005272971.3; XM_006711483.2;
Protein Name B-cell CLL/lymphoma 9 protein
Protein Synonyms/Alias
Gene Name BCL9
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Involved in signal transduction through the Wnt pathway. Promotes beta-catenin's transcriptional activity (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 64 (View all)
PositionPeptidesSourceReferences ( PMIDs )
10SSNPKVRSSPSGNTQcurated20363803; 25849741
11SNPKVRSSPSGNTQSPhosphoSitePlus;curated22135298; 22817900; 25849741
18SPSGNTQSSPKSKQEcurated22817900; 20363803; 25849741
19PSGNTQSSPKSKQEVPhosphoSitePlus;curated22135298; 22817900; 25849741
32EVMVRPPTVMSPSGNPhosphoSitePlus;curated22135298; 26074081
35VRPPTVMSPSGNPQLPhosphoPep 2.0;PhosphoSitePlus;curated19060867; 22135298; 25850435; 25627689; 26074081
47PQLDSKFSNQGKQGGPhosphoSitePlus22135298
62SASQSQPSPCDSKSGcurated25849741; 25262027
66SQPSPCDSKSGGHTPdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated18491316; 16381945; 23193290; 18988627; 22135298; 22817900
82ALPGPGGSMGLKNGAPhosphoSitePlus22135298
102GKGKRERSISADSFDcurated23898821
104GKRERSISADSFDQRdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated19690332; 16381945; 23193290; 19664994; 18988627; 22135298;
107ERSISADSFDQRDPGPhosphoSitePlus;curated22135298; 19690332
115FDQRDPGTPNDDSDIPhosphoPep 2.0;PhosphoSitePlus;curated19060867; 22135298; 25850435; 25627689; 23898821; 23663014;
120PGTPNDDSDIKECNSPhosphoSitePlus22135298
133NSADHIKSQDSQHTPPhosphoSitePlus22135298
136DHIKSQDSQHTPHSMPhosphoSitePlus22135298
139KSQDSQHTPHSMTPSPhosphoSitePlus22135298
144QHTPHSMTPSNATAPPhosphoSitePlus22135298
153SNATAPRSSTPSHGQPhosphoPep 2.0;PhosphoSitePlus;curated19060867; 22135298; 25627689; 23898821; 23663014
Sequence
(Fasta)		MHSSNPKVRS SPSGNTQSSP KSKQEVMVRP PTVMSPSGNP QLDSKFSNQG KQGGSASQSQ 60
PSPCDSKSGG HTPKALPGPG GSMGLKNGAG NGAKGKGKRE RSISADSFDQ RDPGTPNDDS 120
DIKECNSADH IKSQDSQHTP HSMTPSNATA PRSSTPSHGQ TTATEPTPAQ KTPAKVVYVF 180
STEMANKAAE AVLKGQVETI VSFHIQNISN NKTERSTAPL NTQISALRND PKPLPQQPPA 240
PANQDQNSSQ NTRLQPTPPI PAPAPKPAAP PRPLDRESPG VENKLIPSVG SPASSTPLPP 300
DGTGPNSTPN NRAVTPVSQG SNSSSADPKA PPPPPVSSGE PPTLGENPDG LSQEQLEHRE 360
RSLQTLRDIQ RMLFPDEKEF TGAQSGGPQQ NPGVLDGPQK KPEGPIQAMM AQSQSLGKGP 420
GPRTDVGAPF GPQGHRDVPF SPDEMVPPSM NSQSGTIGPD HLDHMTPEQI AWLKLQQEFY 480
EEKRRKQEQV VVQQCSLQDM MVHQHGPRGV VRGPPPPYQM TPSEGWAPGG TEPFSDGINM 540
PHSLPPRGMA PHPNMPGSQM RLPGFAGMIN SEMEGPNVPN PASRPGLSGV SWPDDVPKIP 600
DGRNFPPGQG IFSGPGRGER FPNPQGLSEE MFQQQLAEKQ LGLPPGMAME GIRPSMEMNR 660
MIPGSQRHME PGNNPIFPRI PVEGPLSPSR GDFPKGIPPQ MGPGRELEFG MVPSGMKGDV 720
NLNVNMGSNS QMIPQKMREA GAGPEEMLKL RPGGSDMLPA QQKMVPLPFG EHPQQEYGMG 780
PRPFLPMSQG PGSNSGLRNL REPIGPDQRT NSRLSHMPPL PLNPSSNPTS LNTAPPVQRG 840
LGRKPLDISV AGSQVHSPGI NPLKSPTMHQ VQSPMLGSPS GNLKSPQTPS QLAGMLAGPA 900
AAASIKSPPV LGSAAASPVH LKSPSLPAPS PGWTSSPKPP LQSPGIPPNH KAPLTMASPA 960
MLGNVESGGP PPPTASQPAS VNIPGSLPSS TPYTMPPEPT LSQNPLSIMM SRMSKFAMPS 1020
STPLYHDAIK TVASSDDDSP PARSPNLPSM NNMPGMGINT QNPRISGPNP VVPMPTLSPM 1080
GMTQPLSHSN QMPSPNAVGP NIPPHGVPMG PGLMSHNPIM GHGSQEPPMV PQGRMGFPQG 1140
FPPVQSPPQQ VPFPHNGPSG GQGSFPGGMG FPGEGPLGRP SNLPQSSADA ALCKPGGPGG 1200
PDSFTVLGNS MPSVFTDPDL QEVIRPGATG IPEFDLSRII PSEKPSQTLQ YFPRGEVPGR 1260
KQPQGPGPGF SHMQGMMGEQ APRMGLALPG MGGPGPVGTP DIPLGTAPSM PGHNPMRPPA 1320
FLQQGMMGPH HRMMSPAQST MPGQPTLMSN PAAAVGMIPG KDRGPAGLYT HPGPVGSPGM 1380
MMSMQGMMGP QQNIMIPPQM RPRGMAADVG MGGFSQGPGN PGNMMF 1427
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0160--Chromosomal rearrangement
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-0656--Proto-oncogene
KW-1185--Reference proteome
KW-0879--Wnt signaling pathway
Interpro

IPR015668--Bcl-9
IPR024670--BCL9_beta-catenin-bd_dom
PROSITE
Pfam

PF11502--BCL9
Gene Ontology

GO:0005801--C:cis-Golgi network
GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0060070--P:canonical Wnt signaling pathway
GO:0014908--P:myotube differentiation involved in skeletal muscle regeneration
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0035914--P:skeletal muscle cell differentiation
GO:0035019--P:somatic stem cell population maintenance