dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000104
Uniprot Accession O00471; EXOC5_HUMAN; B2R6C5;
Genbank Protein ID NP_006535.1;
Genbank Nucleotide ID NM_006544.3;
Protein Name Exocyst complex component 5
Protein Synonyms/Alias Exocyst complex component Sec10;hSec10;
Gene Name EXOC5
Gene Synonyms/Alias SEC10;SEC10L1;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
3-----MATTAELFEEdbPTM 3.0;HPRD 9;PhosphoSitePlus18491316; 16381945; 23193290; 18988627; 22135298
4----MATTAELFEEPdbPTM 3.0;HPRD 918491316; 16381945; 23193290; 18988627
122DQLEGVNTPRQRAVEdbPTM 3.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18691976; 16381945; 23193290; 18988627; 21081558; 19060867;
147FLDGELKSDVFTNSEPhosphoSitePlus22135298
210AQRRGEISRMREVAAPhosphoSitePlus22135298
225VLLHFKGYSHCVDVYPhosphoSitePlus22135298
328LMEFNLGTDKQTFLSdbPTM 3.0;PhosphoSitePlus;curated21406692; 16381945; 23193290; 22135298; 22817900
332NLGTDKQTFLSKLIKPhosphoSitePlus22135298
Sequence
(Fasta)		MATTAELFEE PFVADEYIER LVWRTPGGGS RGGPEAFDPK RLLEEFVNHI QELQIMDERI 60
QRKVEKLEQQ CQKEAKEFAK KVQELQKSNQ VAFQHFQELD EHISYVATKV CHLGDQLEGV 120
NTPRQRAVEA QKLMKYFNEF LDGELKSDVF TNSEKIKEAA DIIQKLHLIA QELPFDRFSE 180
VKSKIASKYH DLECQLIQEF TSAQRRGEIS RMREVAAVLL HFKGYSHCVD VYIKQCQEGA 240
YLRNDIFEDA GILCQRVNKQ VGDIFSNPET VLAKLIQNVF EIKLQSFVKE QLEECRKSDA 300
EQYLKNLYDL YTRTTNLSSK LMEFNLGTDK QTFLSKLIKS IFISYLENYI EVETGYLKSR 360
SAMILQRYYD SKNHQKRSIG TGGIQDLKER IRQRTNLPLG PSIDTHGETF LSQEVVVNLL 420
QETKQAFERC HRLSDPSDLP RNAFRIFTIL VEFLCIEHID YALETGLAGI PSSDSRNANL 480
YFLDVVQQAN TIFHLFDKQF NDHLMPLISS SPKLSECLQK KKEIIEQMEM KLDTGIDRTL 540
NCMIGQMKHI LAAEQKKTDF KPEDENNVLI QYTNACVKVC AYVRKQVEKI KNSMDGKNVD 600
TVLMELGVRF HRLIYEHLQQ YSYSCMGGML AICDVAEYRK CAKDFKIPMV LHLFDTLHAL 660
CNLLVVAPDN LKQVCSGEQL ANLDKNILHS FVQLRADYRS ARLARHFS 709
Keyword

KW-0007--Acetylation
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0268--Exocytosis
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
Interpro

IPR009976--Sec10-like
PROSITE
Pfam

PF07393--Sec10
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0017160--F:Ral GTPase binding
GO:0044267--P:cellular protein metabolic process
GO:0006887--P:exocytosis
GO:0061024--P:membrane organization
GO:0006996--P:organelle organization
GO:0006892--P:post-Golgi vesicle-mediated transport
GO:0015031--P:protein transport
GO:0048278--P:vesicle docking