| Tag |
Content |
| dbPAF ID |
dbPAF-0000096 |
| Uniprot Accession |
O00458; IFRD1_HUMAN; B7Z5G1; O75234; Q5U013; Q9BVE4;
|
| Genbank Protein ID |
NP_001007246.1; NP_001184008.1; NP_001184009.1; NP_001541.2;
|
| Genbank Nucleotide ID |
NM_001007245.2; NM_001197079.1; NM_001197080.1; NM_001550.3;
|
| Protein Name |
Interferon-related developmental regulator 1 |
| Protein Synonyms/Alias |
Nerve growth factor-inducible protein PC4; |
| Gene Name |
IFRD1 |
| Gene Synonyms/Alias |
|
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal (By similarity).Functional Description
Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal (By similarity). |
Phosphorylation Sites
|
dbPAF PTMs: 5 |
Sequence
(Fasta) | MPKNKKRNTP HRGSSAGGGG SGAAAATAAT AGGQHRNVQP FSDEDASIET MSHCSGYSDP 60
SSFAEDGPEV LDEEGTQEDL EYKLKGLIDL TLDKSAKTRQ AALEGIKNAL ASKMLYEFIL 120
ERRMTLTDSI ERCLKKGKSD EQRAAAALAS VLCIQLGPGI ESEEILKTLG PILKKIICDG 180
SASMQARQTC ATCFGVCCFI ATDDITELYS TLECLENIFT KSYLKEKDTT VICSTPNTVL 240
HISSLLAWTL LLTICPINEV KKKLEMHFHK LPSLLSCDDV NMRIAAGESL ALLFELARGI 300
ESDFFYEDME SLTQMLRALA TDGNKHRAKV DKRKQRSVFR DVLRAVEERD FPTETIKFGP 360
ERMYIDCWVK KHTYDTFKEV LGSGMQYHLQ SNEFLRNVFE LGPPVMLDAA TLKTMKISRF 420
ERHLYNSAAF KARTKARSKC RDKRADVGEF F
452Fasta Sequence
>O00458|IFRD1|Homo sapiens(Human)
MPKNKKRNTPHRGSSAGGGGSGAAAATAATAGGQHRNVQPFSDEDASIETMSHCSGYSDPSSFAEDGPEVLDEEGTQEDLEYKLKGLIDLTLDKSAKTRQAALEGIKNALASKMLYEFILERRMTLTDSIERCLKKGKSDEQRAAAALASVLCIQLGPGIESEEILKTLGPILKKIICDGSASMQARQTCATCFGVCCFIATDDITELYSTLECLENIFTKSYLKEKDTTVICSTPNTVLHISSLLAWTLLLTICPINEVKKKLEMHFHKLPSLLSCDDVNMRIAAGESLALLFELARGIESDFFYEDMESLTQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVEERDFPTETIKFGPERMYIDCWVKKHTYDTFKEVLGSGMQYHLQSNEFLRNVFELGPPVMLDAATLKTMKISRFERHLYNSAAFKARTKARSKCRDKRADVGEFF
|
| Keyword |
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0621--Polymorphism
KW-1185--Reference proteome
|
| Interpro |
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR006921--Interferon-rel_develop_reg_C
IPR007701--Interferon-rel_develop_reg_N
|
| PROSITE |
|
| Pfam |
PF05004--IFRD
PF04836--IFRD_C
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0007518--P:myoblast fate determination
GO:0030517--P:negative regulation of axon extension
GO:0048671--P:negative regulation of collateral sprouting
GO:0043403--P:skeletal muscle tissue regeneration
GO:0014706--P:striated muscle tissue development
|
