dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0000095 |
| Uniprot Accession | O00453; LST1_HUMAN; B0S8E0; B0S8E1; B0S8E5; O00452; O00454; Q13669; Q2HNT3; Q5HYS9; Q5SP24; Q5STA5; Q5STA6; Q5STA7; Q5STA8; Q5STW6; Q9UJR5; Q9UJR6; Q9UJR7; Q9UJR8; Q9UJS1; |
| Genbank Protein ID | NP_001160010.1; NP_009092.3; NP_995309.2; NP_995310.2; NP_995311.2; NP_995312.2; XP_006715273.1; XP_006725111.1; XP_006725589.1; XP_006725808.1; XP_006725915.1; XP_006726004.1; XP_006726105.1; XP_006726193.1; |
| Genbank Nucleotide ID | NM_001166538.1; NM_007161.3; NM_205837.2; NM_205838.2; NM_205839.2; NM_205840.2; XM_006715210.2; XM_006725048.2; XM_006725526.2; XM_006725745.2; XM_006725852.2; XM_006725941.2; XM_006726042.2; XM_006726130.2; |
| Protein Name | Leukocyte-specific transcript 1 protein |
| Protein Synonyms/Alias | Protein B144; |
| Gene Name | LST1 |
| Gene Synonyms/Alias | B144; |
| Organism | Homo sapiens(Human) |
| NCBI Taxa ID | 9606 |
| Functional Description (View all) |
Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation. |
| Phosphorylation Sites |
dbPAF PTMs: 3 |
| Sequence (Fasta) | MLSRNDDICI YGGLGLGGLL LLAVVLLSAC LCWLHRRVKR LERSWAQGSS EQELHYASLQ 60 RLPVPSSEGP DLRGRDKRGT KEDPRADYAC IAENKPT 98 |
| Keyword | KW-0025--Alternative splicing |
| Interpro | IPR007775--Leukocyte-sp_tscrpt_1_LST1 |
| PROSITE | |
| Pfam | PF05083--LST1 |
| Gene Ontology | GO:0005737--C:cytoplasm |