| Tag |
Content |
| dbPAF ID |
dbPAF-0000078 |
| Uniprot Accession |
O00400; ACATN_HUMAN; B2R5Q2; D3DNK4;
|
| Genbank Protein ID |
NP_001177921.1; NP_004724.1;
|
| Genbank Nucleotide ID |
NM_001190992.1; NM_004733.3;
|
| Protein Name |
Acetyl-coenzyme A transporter 1 |
| Protein Synonyms/Alias |
|
| Gene Name |
SLC33A1 |
| Gene Synonyms/Alias |
ACATN;AT1; |
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).Functional Description
Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622). |
Phosphorylation Sites
|
dbPAF PTMs: 7 |
Sequence
(Fasta) | MSPTISHKDS SRQRRPGNFS HSLDMKSGPL PPGGWDDSHL DSAGREGDRE ALLGDTGTGD 60
FLKAPQSFRA ELSSILLLLF LYVLQGIPLG LAGSIPLILQ SKNVSYTDQA FFSFVFWPFS 120
LKLLWAPLVD AVYVKNFGRR KSWLVPTQYI LGLFMIYLST QVDRLLGNTD DRTPDVIALT 180
VAFFLFEFLA ATQDIAVDGW ALTMLSRENV GYASTCNSVG QTAGYFLGNV LFLALESADF 240
CNKYLRFQPQ PRGIVTLSDF LFFWGTVFLI TTTLVALLKK ENEVSVVKEE TQGITDTYKL 300
LFAIIKMPAV LTFCLLILTA KIGFSAADAV TGLKLVEEGV PKEHLALLAV PMVPLQIILP 360
LIISKYTAGP QPLNTFYKAM PYRLLLGLEY ALLVWWTPKV EHQGGFPIYY YIVVLLSYAL 420
HQVTVYSMYV SIMAFNAKVS DPLIGGTYMT LLNTVSNLGG NWPSTVALWL VDPLTVKECV 480
GASNQNCRTP DAVELCKKLG GSCVTALDGY YVESIICVFI GFGWWFFLGP KFKKLQDEGS 540
SSWKCKRNN
Fasta Sequence
>O00400|SLC33A1|Homo sapiens(Human)
MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGDFLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFSLKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALTVAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADFCNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKLLFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILPLIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYALHQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECVGASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGSSSWKCKRNN
|
| Keyword |
KW-0898--Cataract
KW-0181--Complete proteome
KW-0209--Deafness
KW-0225--Disease mutation
KW-0256--Endoplasmic reticulum
KW-0325--Glycoprotein
KW-0890--Hereditary spastic paraplegia
KW-0472--Membrane
KW-0523--Neurodegeneration
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
|
| Interpro |
IPR024371--Acetyl-CoA_trnpstr_1
IPR004752--AmpG_permease/AT-1
IPR020846--MFS_dom
|
| PROSITE |
|
| Pfam |
PF13000--Acatn
|
| Gene Ontology |
GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0005887--C:integral component of plasma membrane
GO:0016020--C:membrane
GO:0008521--F:acetyl-CoA transporter activity
GO:0015295--F:solute:proton symporter activity
GO:0015876--P:acetyl-CoA transport
GO:0030509--P:BMP signaling pathway
GO:0015992--P:proton transport
GO:0060395--P:SMAD protein signal transduction
GO:0055085--P:transmembrane transport
GO:0006810--P:transport
|
