dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000072
Uniprot Accession O00339; MATN2_HUMAN; A8K106; E7EW74; E9PD48; E9PGL2; Q6UWA5; Q7Z5X1; Q8NDE6; Q96FT5; Q9NSZ1;
Genbank Protein ID NP_002371.3; NP_085072.2; XP_011515340.1;
Genbank Nucleotide ID NM_002380.3; NM_030583.2; XM_011517038.1;
Protein Name Matrilin-2
Protein Synonyms/Alias
Gene Name MATN2
Gene Synonyms/Alias UNQ193/PRO219;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Involved in matrix assembly.
Phosphorylation Sites
 dbPAF PTMs: 12
PositionPeptidesSourceReferences ( PMIDs )
101TRVGLLQYGSTVKNEPhosphoSitePlus22135298
134MRHLSTGTMTGLAIQPhosphoSitePlus22135298
136HLSTGTMTGLAIQYAPhosphoSitePlus22135298
149YALNIAFSEAEGARPPhosphoSitePlus22135298
169PRVIMIVTDGRPQDSPhosphoSitePlus22135298
432YCRCHRGYTLDPNGKPhosphoSitePlus22135298
705QYSTQVHTEFTLRNFPhosphoSitePlus22135298
714FTLRNFNSAKDMKKAPHOSIDA21081558
894EEDNLLRSTQKLSHSdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;curated17525332; 16381945; 23193290; 18988627; 22135298; 22817900
895EDNLLRSTQKLSHSTdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;curated17525332; 16381945; 23193290; 18988627; 22135298; 22817900
901STQKLSHSTKPSGSPPhosphoSitePlus22135298
902TQKLSHSTKPSGSPLPhosphoSitePlus22135298
Sequence
(Fasta)		MEKMLAGCFL LILGQIVLLP AEARERSRGR SISRGRHART HPQTALLESS CENKRADLVF 60
IIDSSRSVNT HDYAKVKEFI VDILQFLDIG PDVTRVGLLQ YGSTVKNEFS LKTFKRKSEV 120
ERAVKRMRHL STGTMTGLAI QYALNIAFSE AEGARPLREN VPRVIMIVTD GRPQDSVAEV 180
AAKARDTGIL IFAIGVGQVD FNTLKSIGSE PHEDHVFLVA NFSQIETLTS VFQKKLCTAH 240
MCSTLEHNCA HFCINIPGSY VCRCKQGYIL NSDQTTCRIQ DLCAMEDHNC EQLCVNVPGS 300
FVCQCYSGYA LAEDGKRCVA VDYCASENHG CEHECVNADG SYLCQCHEGF ALNPDKKTCT 360
KIDYCASSNH GCQHECVNTD DSYSCHCLKG FTLNPDKKTC RRINYCALNK PGCEHECVNM 420
EESYYCRCHR GYTLDPNGKT CSRVDHCAQQ DHGCEQLCLN TEDSFVCQCS EGFLINEDLK 480
TCSRVDYCLL SDHGCEYSCV NMDRSFACQC PEGHVLRSDG KTCAKLDSCA LGDHGCEHSC 540
VSSEDSFVCQ CFEGYILRED GKTCRRKDVC QAIDHGCEHI CVNSDDSYTC ECLEGFRLAE 600
DGKRCRRKDV CKSTHHGCEH ICVNNGNSYI CKCSEGFVLA EDGRRCKKCT EGPIDLVFVI 660
DGSKSLGEEN FEVVKQFVTG IIDSLTISPK AARVGLLQYS TQVHTEFTLR NFNSAKDMKK 720
AVAHMKYMGK GSMTGLALKH MFERSFTQGE GARPLSTRVP RAAIVFTDGR AQDDVSEWAS 780
KAKANGITMY AVGVGKAIEE ELQEIASEPT NKHLFYAEDF STMDEISEKL KKGICEALED 840
SDGRQDSPAG ELPKTVQQPT ESEPVTINIQ DLLSCSNFAV QHRYLFEEDN LLRSTQKLSH 900
STKPSGSPLE EKHDQCKCEN LIMFQNLANE EVRKLTQRLE EMTQRMEALE NRLRYR 957
Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0245--EGF-like domain
KW-0325--Glycoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0964--Secreted
KW-0732--Signal
Interpro

IPR026823--cEGF
IPR001881--EGF-like_Ca-bd_dom
IPR013032--EGF-like_CS
IPR000742--EGF-like_dom
IPR000152--EGF-type_Asp/Asn_hydroxyl_site
IPR009030--Growth_fac_rcpt_N_dom
IPR019466--Matrilin_coiled-coil_trimer
IPR002035--VWF_A
PROSITE

PS00010--ASX_HYDROXYL
PS01186--EGF_2
PS50026--EGF_3
PS50234--VWFA
Pfam

PF12662--cEGF
PF07645--EGF_CA
PF10393--Matrilin_ccoil
PF00092--VWA
Gene Ontology

GO:0005604--C:basement membrane
GO:0005578--C:proteinaceous extracellular matrix
GO:0005509--F:calcium ion binding
GO:0007411--P:axon guidance
GO:0031104--P:dendrite regeneration
GO:0008347--P:glial cell migration
GO:0001764--P:neuron migration
GO:0048678--P:response to axon injury