dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0000071 | ||||||||
| Uniprot Accession | O00338; ST1C2_HUMAN; B2R813; Q53SG4; | ||||||||
| Genbank Protein ID | NP_001047.1; NP_789795.1; | ||||||||
| Genbank Nucleotide ID | NM_001056.3; NM_176825.2; | ||||||||
| Protein Name | Sulfotransferase 1C2 | ||||||||
| Protein Synonyms/Alias | |||||||||
| Gene Name | SULT1C2 | ||||||||
| Gene Synonyms/Alias | SULT1C1; | ||||||||
| Organism | Homo sapiens(Human) | ||||||||
| NCBI Taxa ID | 9606 | ||||||||
| Functional Description (View all) |
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hyroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MALTSDLGKQ IKLKEVEGTL LQPATVDNWS QIQSFEAKPD DLLICTYPKA GTTWIQEIVD 60 MIEQNGDVEK CQRAIIQHRH PFIEWARPPQ PSGVEKAKAM PSPRILKTHL STQLLPPSFW 120 ENNCKFLYVA RNAKDCMVSY YHFQRMNHML PDPGTWEEYF ETFINGKVVW GSWFDHVKGW 180 WEMKDRHQIL FLFYEDIKRD PKHEIRKVMQ FMGKKVDETV LDKIVQETSF EKMKENPMTN 240 RSTVSKSILD QSISSFMRKG TVGDWKNHFT VAQNERFDEI YRRKMEGTSI NFCMEL 297 |
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| Keyword | KW-0002--3D-structure |
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| Interpro | |||||||||
| PROSITE | |||||||||
| Pfam | PF00685--Sulfotransfer_1 |
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| Gene Ontology | GO:0005737--C:cytoplasm |