| Tag |
Content |
| dbPAF ID |
dbPAF-0000066 |
| Uniprot Accession |
O00321; ETV2_HUMAN; A6NFN5; B3KUL0; B9EIN1; Q9UEA0;
|
| Genbank Protein ID |
NP_055024.2; XP_005258709.1;
|
| Genbank Nucleotide ID |
NM_014209.3; XM_005258652.2;
|
| Protein Name |
ETS translocation variant 2 |
| Protein Synonyms/Alias |
Ets-related protein 71; |
| Gene Name |
ETV2 |
| Gene Synonyms/Alias |
ER71;ETSRP71; |
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.Functional Description
Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'. |
Phosphorylation Sites
|
dbPAF PTMs: 5 |
Sequence
(Fasta) | MDLWNWDEAS PQEVPPGNKL AGLEGAKLGF CFPDLALQGD TPTATAETCW KGTSSSLASF 60
PQLDWGSALL HPEVPWGAEP DSQALPWSGD WTDMACTAWD SWSGASQTLG PAPLGPGPIP 120
AAGSEGAAGQ NCVPVAGEAT SWSRAQAAGS NTSWDCSVGP DGDTYWGSGL GGEPRTDCTI 180
SWGGPAGPDC TTSWNPGLHA GGTTSLKRYQ SSALTVCSEP SPQSDRASLA RCPKTNHRGP 240
IQLWQFLLEL LHDGARSSCI RWTGNSREFQ LCDPKEVARL WGERKRKPGM NYEKLSRGLR 300
YYYRRDIVRK SGGRKYTYRF GGRVPSLAYP DCAGGGRGAE TQ
343Fasta Sequence
>O00321|ETV2|Homo sapiens(Human)
MDLWNWDEASPQEVPPGNKLAGLEGAKLGFCFPDLALQGDTPTATAETCWKGTSSSLASFPQLDWGSALLHPEVPWGAEPDSQALPWSGDWTDMACTAWDSWSGASQTLGPAPLGPGPIPAAGSEGAAGQNCVPVAGEATSWSRAQAAGSNTSWDCSVGPDGDTYWGSGLGGEPRTDCTISWGGPAGPDCTTSWNPGLHAGGTTSLKRYQSSALTVCSEPSPQSDRASLARCPKTNHRGPIQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGRVPSLAYPDCAGGGRGAETQ
|
| Keyword |
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome
|
| Interpro |
IPR000418--Ets_dom
IPR011991--WHTH_DNA-bd_dom
|
| PROSITE |
PS00345--ETS_DOMAIN_1
PS00346--ETS_DOMAIN_2
PS50061--ETS_DOMAIN_3
|
| Pfam |
PF00178--Ets
|
| Gene Ontology |
GO:0005634--C:nucleus
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001824--P:blastocyst development
GO:0048514--P:blood vessel morphogenesis
GO:0060803--P:BMP signaling pathway involved in mesodermal cell fate specification
GO:0030154--P:cell differentiation
GO:0030218--P:erythrocyte differentiation
GO:0007219--P:Notch signaling pathway
GO:0001890--P:placenta development
GO:0045603--P:positive regulation of endothelial cell differentiation
GO:2000382--P:positive regulation of mesoderm development
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0016055--P:Wnt signaling pathway
|
