dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000055
Uniprot Accession O00287; RFXAP_HUMAN; B2R9T8; Q5VZM6; Q8TC40;
Genbank Protein ID NP_000529.1;
Genbank Nucleotide ID NM_000538.3;
Protein Name Regulatory factor X-associated protein
Protein Synonyms/Alias
Gene Name RFXAP
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Part of the RFX complex that binds to the X-box of MHC II promoters.
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
118LEDEETHSGGEGSSGdbPTM 3.0;HPRD 9;PhosphoSitePlus18452278; 16381945; 23193290; 18988627; 22135298
132GGARRRGSGGGSMSKcurated22798277
138GSGGGSMSKTCTYEGPhosphoSitePlus22135298
143SMSKTCTYEGCSETTPhosphoSitePlus22135298
190LNCGGTASTGSAGNVcurated25627689
193GGTASTGSAGNVKLEcurated25627689
237VLNQKRLSLLRSPEVPhosphoSitePlus;curated22135298; 25627689; 26074081; 24702127
241KRLSLLRSPEVVQFLPhosphoSitePlus;curated22135298; 25627689
Sequence
(Fasta)		MEAQGVAEGA GPGAASGVPH PAALAPAAAP TLAPASVAAA ASQFTLLVMQ PCAGQDEAAA 60
PGGSVGAGKP VRYLCEGAGD GEEEAGEDEA DLLDTSDPPG GGESAASLED LEDEETHSGG 120
EGSSGGARRR GSGGGSMSKT CTYEGCSETT SQVAKQRKPW MCKKHRNKMY KDKYKKKKSD 180
QALNCGGTAS TGSAGNVKLE ESADNILSIV KQRTGSFGDR PARPTLLEQV LNQKRLSLLR 240
SPEVVQFLQK QQQLLNQQVL EQRQQQFPGT SM 273
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0238--DNA-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0705--SCID
Interpro

IPR029316--RFXAP_RFXANK-bd
PROSITE
Pfam

PF15289--RFXA_RFXANK_bdg
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0003713--F:transcription coactivator activity
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0045893--P:positive regulation of transcription, DNA-templated