dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000051
Uniprot Accession O00264; PGRC1_HUMAN; B7Z1L3; Q9UGJ9;
Genbank Protein ID NP_001269550.1; NP_006658.1;
Genbank Nucleotide ID NM_001282621.1; NM_006667.4;
Protein Name Membrane-associated progesterone receptor component 1
Protein Synonyms/Alias
Gene Name PGRMC1
Gene Synonyms/Alias HPR6.6;PGRMC;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Receptor for progesterone.
Phosphorylation Sites
 dbPAF PTMs: 13
PositionPeptidesSourceReferences ( PMIDs )
54RGDQPAASGDSDDDEdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18691976; 19369195; 19690332; 16381945; 23193290; 18578522;
57QPAASGDSDDDEPPPdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated15302935; 17081983; 17287340; 18318008; 18669648; 18691976;
74RLKRRDFTPAELRRFdbPTM 3.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18669648; 18691976; 16381945; 23193290; 20166139; 18988627;
101NGKVFDVTKGRKFYGPhosphoSitePlus22135298
107VTKGRKFYGPEGPYGPhosphoSitePlus22135298
113FYGPEGPYGVFAGRDdbPTM 3.0;PhosphoSitePlus21253578; 16381945; 23193290; 22135298
139KEALKDEYDDLSDLTPhosphoSitePlus22135298
143KDEYDDLSDLTAAQQPhosphoSitePlus22135298
152LTAAQQETLSDWESQPhosphoSitePlus22135298
178LKEGEEPTVYSDEEEdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;curated19369195; 19413330; 16381945; 23193290; 18491316; 20166139;
180EGEEPTVYSDEEEPKdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;curated17081983; 19369195; 16381945; 23193290; 18083107; 20562096;
181GEEPTVYSDEEEPKDdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated15302935; 16565220; 17081983; 17287340; 17487921; 17924679;
190EEEPKDESARKND--dbPTM 3.0;HPRD 9;PhosphoSitePlus;SysPTM 2.0;curated17081983; 16381945; 23193290; 18988627; 22135298; 19366988;
Sequence
(Fasta)		MAAEDVVATG ADPSDLESGG LLHEIFTSPL NLLLLGLCIF LLYKIVRGDQ PAASGDSDDD 60
EPPPLPRLKR RDFTPAELRR FDGVQDPRIL MAINGKVFDV TKGRKFYGPE GPYGVFAGRD 120
ASRGLATFCL DKEALKDEYD DLSDLTAAQQ ETLSDWESQF TFKYHHVGKL LKEGEEPTVY 180
SDEEEPKDES ARKND 196
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0256--Endoplasmic reticulum
KW-0446--Lipid-binding
KW-0472--Membrane
KW-0492--Microsome
KW-0597--Phosphoprotein
KW-0675--Receptor
KW-1185--Reference proteome
KW-0754--Steroid-binding
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR001199--Cyt_B5-like_heme/steroid-bd
PROSITE
Pfam

PF00173--Cyt-b5
Gene Ontology

GO:0012505--C:endomembrane system
GO:0005783--C:endoplasmic reticulum
GO:0005789--C:endoplasmic reticulum membrane
GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0016020--C:membrane
GO:0005730--C:nucleolus
GO:0020037--F:heme binding
GO:0005496--F:steroid binding
GO:0007411--P:axon guidance