dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000050
Uniprot Accession O00258; WRB_HUMAN; A8KAP8; A8MQ44; D3DSH9; O60740;
Genbank Protein ID NP_001139690.1; NP_004618.2; XP_005261116.1; XP_005261117.1; XP_005261118.1; XP_011528047.1;
Genbank Nucleotide ID NM_001146218.1; NM_004627.4; XM_005261059.2; XM_005261060.2; XM_005261061.2; XM_011529745.1;
Protein Name Tail-anchored protein insertion receptor WRB
Protein Synonyms/Alias Congenital heart disease 5 protein;Tryptophan-rich basic protein;WRB;
Gene Name WRB
Gene Synonyms/Alias CHD5;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Receptor for ASNA1/TRC40-mediated insertion of tail-anchored (TA) proteins into the ER membrane.
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
30VLRILLPSFSSFMSRPhosphoSitePlus22135298
47QKDAEQESQMRAEIQPhosphoSitePlus22135298
94KTHVKARTAQLAKIKPhosphoSitePlus22135298
Sequence
(Fasta)		MSSAAADHWA WLLVLSFVFG CNVLRILLPS FSSFMSRVLQ KDAEQESQMR AEIQDMKQEL 60
STVNMMDEFA RYARLERKIN KMTDKLKTHV KARTAQLAKI KWVISVAFYV LQAALMISLI 120
WKYYSVPVAV VPSKWITPLD RLVAFPTRVA GGVGITCWIL VCNKVVAIVL HPFS 175
Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0472--Membrane
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR028945--WRB/Get1
PROSITE
Pfam

PF04420--CHD5
Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0005634--C:nucleus
GO:0071816--P:tail-anchored membrane protein insertion into ER membrane