| Tag |
Content |
| dbPAF ID |
dbPAF-0000047 |
| Uniprot Accession |
O00254; PAR3_HUMAN; B2R754; B4DQ13; Q52M68; Q7Z3W3;
|
| Genbank Protein ID |
NP_001243495.1; NP_004092.1;
|
| Genbank Nucleotide ID |
NM_001256566.1; NM_004101.3;
|
| Protein Name |
Proteinase-activated receptor 3 |
| Protein Synonyms/Alias |
|
| Gene Name |
F2RL2 |
| Gene Synonyms/Alias |
PAR3; |
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.Functional Description
Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. |
Phosphorylation Sites
|
dbPAF PTMs: 2 |
Sequence
(Fasta) | MKALIFAAAG LLLLLPTFCQ SGMENDTNNL AKPTLPIKTF RGAPPNSFEE FPFSALEGWT 60
GATITVKIKC PEESASHLHV KNATMGYLTS SLSTKLIPAI YLLVFVVGVP ANAVTLWMLF 120
FRTRSICTTV FYTNLAIADF LFCVTLPFKI AYHLNGNNWV FGEVLCRATT VIFYGNMYCS 180
ILLLACISIN RYLAIVHPFT YRGLPKHTYA LVTCGLVWAT VFLYMLPFFI LKQEYYLVQP 240
DITTCHDVHN TCESSSPFQL YYFISLAFFG FLIPFVLIIY CYAAIIRTLN AYDHRWLWYV 300
KASLLILVIF TICFAPSNII LIIHHANYYY NNTDGLYFIY LIALCLGSLN SCLDPFLYFL 360
MSKTRNHSTA YLTK
375Fasta Sequence
>O00254|F2RL2|Homo sapiens(Human)
MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK
|
| Keyword |
KW-0025--Alternative splicing
KW-0094--Blood coagulation
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0297--G-protein coupled receptor
KW-0325--Glycoprotein
KW-0356--Hemostasis
KW-0472--Membrane
KW-0621--Polymorphism
KW-0675--Receptor
KW-1185--Reference proteome
KW-0732--Signal
KW-0807--Transducer
KW-0812--Transmembrane
KW-1133--Transmembrane helix
|
| Interpro |
IPR000276--GPCR_Rhodpsn
IPR017452--GPCR_Rhodpsn_7TM
IPR003943--Prot_act_rcpt_3
IPR003912--Protea_act_rcpt
|
| PROSITE |
PS00237--G_PROTEIN_RECEP_F1_1
PS50262--G_PROTEIN_RECEP_F1_2
|
| Pfam |
PF00001--7tm_1
|
| Gene Ontology |
GO:0016324--C:apical plasma membrane
GO:0005576--C:extracellular region
GO:0005887--C:integral component of plasma membrane
GO:0005886--C:plasma membrane
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0015057--F:thrombin receptor activity
GO:0007596--P:blood coagulation
GO:0030168--P:platelet activation
GO:0009611--P:response to wounding
|
