| Tag |
Content |
| dbPAF ID |
dbPAF-0000046 |
| Uniprot Accession |
O00244; ATOX1_HUMAN; A8KAJ8; D3DQI2; Q2M1R6; Q56AP3;
|
| Genbank Protein ID |
NP_004036.1;
|
| Genbank Nucleotide ID |
NM_004045.3;
|
| Protein Name |
Copper transport protein ATOX1 |
| Protein Synonyms/Alias |
Metal transport protein ATX1; |
| Gene Name |
ATOX1 |
| Gene Synonyms/Alias |
HAH1; |
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense.Functional Description
Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense. |
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MPKHEFSVDM TCGGCAEAVS RVLNKLGGVK YDIDLPNKKV CIESEHSMDT LLATLKKTGK 60
TVSYLGLE
69Fasta Sequence
>O00244|ATOX1|Homo sapiens(Human)
MPKHEFSVDMTCGGCAEAVSRVLNKLGGVKYDIDLPNKKVCIESEHSMDTLLATLKKTGKTVSYLGLE
|
| Keyword |
KW-0002--3D-structure
KW-0007--Acetylation
KW-0143--Chaperone
KW-0181--Complete proteome
KW-0186--Copper
KW-0187--Copper transport
KW-0406--Ion transport
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0813--Transport
|
| Interpro |
IPR017969--Heavy-metal-associated_CS
IPR006121--HMA_dom
|
| PROSITE |
PS01047--HMA_1
PS50846--HMA_2
|
| Pfam |
PF00403--HMA
|
| Gene Ontology |
GO:0005829--C:cytosol
GO:0016531--F:copper chaperone activity
GO:0005507--F:copper ion binding
GO:0005375--F:copper ion transmembrane transporter activity
GO:0032767--F:copper-dependent protein binding
GO:0016530--F:metallochaperone activity
GO:0006878--P:cellular copper ion homeostasis
GO:0006825--P:copper ion transport
GO:0015680--P:intracellular copper ion transport
GO:0006979--P:response to oxidative stress
GO:0000302--P:response to reactive oxygen species
|
