dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0000045 | ||||||||
| Uniprot Accession | O00241; SIRB1_HUMAN; A6NLM2; B2R8V0; Q5TFQ9; Q5TFR0; Q8TB12; Q9H1U5; Q9Y4V0; | ||||||||
| Genbank Protein ID | NP_001077379.1; NP_006056.2; XP_011527434.1; XP_011527435.1; | ||||||||
| Genbank Nucleotide ID | NM_001083910.2; NM_006065.3; XM_011529132.1; XM_011529133.1; | ||||||||
| Protein Name | Signal-regulatory protein beta-1 | ||||||||
| Protein Synonyms/Alias | |||||||||
| Gene Name | SIRPB1 | ||||||||
| Gene Synonyms/Alias | |||||||||
| Organism | Homo sapiens(Human) | ||||||||
| NCBI Taxa ID | 9606 | ||||||||
| Functional Description (View all) |
Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MPVPASWPHL PSPFLLMTLL LGRLTGVAGE DELQVIQPEK SVSVAAGESA TLRCAMTSLI 60 PVGPIMWFRG AGAGRELIYN QKEGHFPRVT TVSELTKRNN LDFSISISNI TPADAGTYYC 120 VKFRKGSPDD VEFKSGAGTE LSVRAKPSAP VVSGPAVRAT PEHTVSFTCE SHGFSPRDIT 180 LKWFKNGNEL SDFQTNVDPA GDSVSYSIHS TARVVLTRGD VHSQVICEIA HITLQGDPLR 240 GTANLSEAIR VPPTLEVTQQ PMRAENQANV TCQVSNFYPR GLQLTWLENG NVSRTETAST 300 LIENKDGTYN WMSWLLVNTC AHRDDVVLTC QVEHDGQQAV SKSYALEISA HQKEHGSDIT 360 HEAALAPTAP LLVALLLGPK LLLVVGVSAI YICWKQKA 399 |
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| Keyword | KW-0002--3D-structure |
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| Interpro | IPR007110--Ig-like_dom |
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| PROSITE | PS50835--IG_LIKE |
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| Pfam | |||||||||
| Gene Ontology | GO:0070062--C:extracellular exosome |