dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000033
Uniprot Accession O00214; LEG8_HUMAN; O15215; Q5T3P5; Q5T3Q4; Q8TEV1; Q96B92; Q9BXC8; Q9H584; Q9H585; Q9UEZ6; Q9UP32; Q9UP33; Q9UP34;
Genbank Protein ID NP_006490.3; NP_963837.1; NP_963838.1; NP_963839.1;
Genbank Nucleotide ID NM_006499.4; NM_201543.2; NM_201544.2; NM_201545.2;
Protein Name Galectin-8
Protein Synonyms/Alias
Gene Name LGALS8
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.
Phosphorylation Sites
 dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
54QVDLQNGSSMKPRADPhosphoSitePlus22135298
55VDLQNGSSMKPRADVPhosphoSitePlus22135298
141KIDTLGIYGKVNIHSPhosphoSitePlus22135298
193PFAARLNTPMGPGRTPhosphoSitePlus22135298
200TPMGPGRTVVVKGEVPhosphoSitePlus22135298
Sequence
(Fasta)		MMLSLNNLQN IIYNPVIPFV GTIPDQLDPG TLIVIRGHVP SDADRFQVDL QNGSSMKPRA 60
DVAFHFNPRF KRAGCIVCNT LINEKWGREE ITYDTPFKRE KSFEIVIMVL KDKFQVAVNG 120
KHTLLYGHRI GPEKIDTLGI YGKVNIHSIG FSFSSDLQST QASSLELTEI SRENVPKSGT 180
PQLRLPFAAR LNTPMGPGRT VVVKGEVNAN AKSFNVDLLA GKSKDIALHL NPRLNIKAFV 240
RNSFLQESWG EEERNITSFP FSPGMYFEMI IYCDVREFKV AVNGVHSLEY KHRFKELSSI 300
DTLEINGDIH LLEVRSW 318
Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0430--Lectin
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR013320--ConA-like_dom
IPR030638--Galectin_8
IPR001079--Galectin_CRD
PROSITE

PS51304--GALECTIN
Pfam

PF00337--Gal-bind_lectin
Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0016020--C:membrane
GO:0030246--F:carbohydrate binding
GO:0002317--P:plasma cell differentiation
GO:0031295--P:T cell costimulation
GO:0098792--P:xenophagy