dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000027
Uniprot Accession O00194; RB27B_HUMAN; B2RAB0; Q9BZB6;
Genbank Protein ID NP_004154.2; XP_005266790.1; XP_005266791.1; XP_011524431.1;
Genbank Nucleotide ID NM_004163.4; XM_005266733.1; XM_005266734.3; XM_011526129.1;
Protein Name Ras-related protein Rab-27B
Protein Synonyms/Alias C25KG;
Gene Name RAB27B
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
May be involved in targeting uroplakins to urothelial apical membranes.
Phosphorylation Sites
dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
2------MTDGDYDYLPhosphoSitePlus22135298
6--MTDGDYDYLIKLLPhosphoSitePlus22135298
53FREKRVVYNAQGPNGcurated25003641
61NAQGPNGSSGKAFKVcurated25003641
83AGQERFRSLTTAFFRPhosphoSitePlus;curated22135298; 23917254
203DTVNGGNSGNLDGEKPhosphoSitePlus;curated22135298; 25627689
Sequence
(Fasta)
MTDGDYDYLI KLLALGDSGV GKTTFLYRYT DNKFNPKFIT TVGIDFREKR VVYNAQGPNG 60
SSGKAFKVHL QLWDTAGQER FRSLTTAFFR DAMGFLLMFD LTSQQSFLNV RNWMSQLQAN 120
AYCENPDIVL IGNKADLPDQ REVNERQARE LADKYGIPYF ETSAATGQNV EKAVETLLDL 180
IMKRMEQCVE KTQIPDTVNG GNSGNLDGEK PPEKKCIC 219
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-1015--Disulfide bond
KW-0342--GTP-binding
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0488--Methylation
KW-0547--Nucleotide-binding
KW-0621--Polymorphism
KW-0636--Prenylation
KW-1185--Reference proteome

Interpro

IPR027417--P-loop_NTPase
IPR005225--Small_GTP-bd_dom
IPR001806--Small_GTPase
IPR003579--Small_GTPase_Rab_type

PROSITE

PS51419--RAB

Pfam

PF00071--Ras

Gene Ontology

GO:0016324--C:apical plasma membrane
GO:0070062--C:extracellular exosome
GO:0005794--C:Golgi apparatus
GO:0005795--C:Golgi stack
GO:0042470--C:melanosome
GO:0032585--C:multivesicular body membrane
GO:0030141--C:secretory granule
GO:0030140--C:trans-Golgi network transport vesicle
GO:0042589--C:zymogen granule membrane
GO:0019003--F:GDP binding
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0031489--F:myosin V binding
GO:0019904--F:protein domain specific binding
GO:0006886--P:intracellular protein transport
GO:0032402--P:melanosome transport
GO:0071985--P:multivesicular body sorting pathway
GO:0045921--P:positive regulation of exocytosis
GO:0009306--P:protein secretion
GO:0032482--P:Rab protein signal transduction
GO:0006904--P:vesicle docking involved in exocytosis