dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000025
Uniprot Accession O00192; ARVC_HUMAN; B7WNV2;
Genbank Protein ID NP_001661.1; XP_006724310.1; XP_011528482.1;
Genbank Nucleotide ID NM_001670.2; XM_006724247.2; XM_011530180.1;
Protein Name Armadillo repeat protein deleted in velo-cardio-facial syndrome
Protein Synonyms/Alias
Gene Name ARVCF
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Involved in protein-protein interactions at adherens junctions.
Phosphorylation Sites
 dbPAF PTMs: 33 (View all)
PositionPeptidesSourceReferences ( PMIDs )
102TVEEDPGTPTSHVSIPhosphoSitePlus;UniProt22135298; 24275569
104EEDPGTPTSHVSIVTPhosphoSitePlus;UniProt22135298; 24275569
105EDPGTPTSHVSIVTSPhosphoSitePlus22135298
108GTPTSHVSIVTSEDGPhosphoSitePlus22135298
111TSHVSIVTSEDGTTRPhosphoSitePlus22135298
185LSRAYLSSGGGFPEGPhosphoSitePlus22135298
198EGPEPRDSPSYGSLSPhosphoSitePlus22135298
200PEPRDSPSYGSLSRGPhosphoSitePlus22135298
201EPRDSPSYGSLSRGLPhosphoSitePlus22135298
203RDSPSYGSLSRGLGMPhosphoSitePlus;curated22135298; 25850435; 24961811
205SPSYGSLSRGLGMRPcurated23403867
249PGPPGGRSLPERFQAPhosphoSitePlus22135298
259ERFQAEPYGLEDDTRPhosphoSitePlus22135298
265PYGLEDDTRSLAADDPhosphoSitePlus;curated22135298; 23090842; 22798277
267GLEDDTRSLAADDEGdbPTM 3.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;UniProt;curated19664994; 20044836; 16381945; 23193290; 15345747; 18988627;
282GPELEPDYGTATRRRdbPTM 3.0;PhosphoSitePlus;curated20007894; 20562096; 20736484; 16381945; 23193290; 22135298;
284ELEPDYGTATRRRPEPhosphoSitePlus;curated22135298; 25849741
332LAQPERGSMGSLDRLdbPTM 3.0;PhosphoSitePlus;UniProt;curated20363803; 16381945; 23193290; 22135298; 24275569; 25219547;
335PERGSMGSLDRLVRRdbPTM 3.0;PhosphoSitePlus;UniProt;curated20363803; 16381945; 23193290; 22135298; 24275569; 25850435;
343LDRLVRRSPSVDSARPhosphoSitePlus;UniProt;curated22135298; 24275569; 23898821; 22798277; 24961811
Sequence
(Fasta)		MEDCNVHSAA SILASVKEQE ARFERLTRAL EQERRHVALQ LERAQQPGMV SGGMGSGQPL 60
PMAWQQLVLQ EQSPGSQASL ATMPEAPDVL EETVTVEEDP GTPTSHVSIV TSEDGTTRRT 120
ETKVTKTVKT VTTRTVRQVP VGPDGLPLLD GGPPLGPFAD GALDRHFLLR GGGPVATLSR 180
AYLSSGGGFP EGPEPRDSPS YGSLSRGLGM RPPRAGPLGP GPGDGCFTLP GHREAFPVGP 240
EPGPPGGRSL PERFQAEPYG LEDDTRSLAA DDEGGPELEP DYGTATRRRP ECGRGLHTRA 300
YEDTADDGGE LADERPAFPM VTAPLAQPER GSMGSLDRLV RRSPSVDSAR KEPRWRDPEL 360
PEVLAMLRHP VDPVKANAAA YLQHLCFENE GVKRRVRQLR GLPLLVALLD HPRAEVRRRA 420
CGALRNLSYG RDTDNKAAIR DCGGVPALVR LLRAARDNEV RELVTGTLWN LSSYEPLKMV 480
IIDHGLQTLT HEVIVPHSGW EREPNEDSKP RDAEWTTVFK NTSGCLRNVS SDGAEARRRL 540
RECEGLVDAL LHALQSAVGR KDTDNKSVEN CVCIMRNLSY HVHKEVPGAD RYQEAEPGPL 600
GSAVGSQRRR RDDASCFGGK KAKEEWFHQG KKDGEMDRNF DTLDLPKRTE AAKGFELLYQ 660
PEVVRLYLSL LTESRNFNTL EAAAGALQNL SAGNWMWATY IRATVRKERG LPVLVELLQS 720
ETDKVVRAVA IALRNLSLDR RNKDLIGSYA MAELVRNVRN AQAPPRPGAC LEEDTVVAVL 780
NTIHEIVSDS LDNARSLLQA RGVPALVALV ASSQSVREAK AASHVLQTVW SYKELRGTLQ 840
KDGWTKARFQ SAAATAKGPK GALSPGGFDD STLPLVDKSL EGEKTGSRDV IPMDALGPDG 900
YSTVDRRERR PRGASSAGEA SEKEPLKLDP SRKAPPPGPS RPAVRLVDAV GDAKPQPVDS 960
WV 963
Keyword

KW-0025--Alternative splicing
KW-0130--Cell adhesion
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000225--Armadillo
IPR028444--ARVCF
IPR028435--Plakophilin/d_Catenin
PROSITE

PS50176--ARM_REPEAT
Pfam

PF00514--Arm
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005622--C:intracellular
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0016339--P:calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007155--P:cell adhesion
GO:0007275--P:multicellular organismal development
GO:0016337--P:single organismal cell-cell adhesion