dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000009
Uniprot Accession O00151; PDLI1_HUMAN; B2RBS6; Q5VZH5; Q9BPZ9;
Genbank Protein ID NP_066272.1;
Genbank Nucleotide ID NM_020992.3;
Protein Name PDZ and LIM domain protein 1
Protein Synonyms/Alias C-terminal LIM domain protein 1;Elfin;LIM domain protein CLP-36;
Gene Name PDLIM1
Gene Synonyms/Alias CLIM1;CLP36;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton.
Phosphorylation Sites
 dbPAF PTMs: 29 (View all)
PositionPeptidesSourceReferences ( PMIDs )
31FEQPLAISRVTPGSKdbPTM 3.0;HPRD 9;curated20068231; 16381945; 23193290; 18988627
34PLAISRVTPGSKAALdbPTM 3.0;HPRD 9;PHOSIDA;PhosphoSitePlus;curated20068231; 16381945; 23193290; 18988627; 21081558; 22135298;
90RSEHKVWSPLVTEEGdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated17924679; 18088087; 18669648; 19413330; 19690332; 16381945;
94KVWSPLVTEEGKRHPPhosphoSitePlus22135298
118QEVLHIGSAHNRSAMdbPTM 3.0;HPRD 9;PHOSIDA;PhosphoSitePlus;curated20068231; 16381945; 23193290; 18988627; 21081558; 22135298;
123IGSAHNRSAMPFTASPhosphoSitePlus;curated22135298; 23911959
128NRSAMPFTASPASSTcurated23403867
130SAMPFTASPASSTTAdbPTM 3.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated17924679; 19413330; 19690332; 16381945; 23193290; 18491316;
133PFTASPASSTTARVIdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;curated18669648; 16381945; 23193290; 19690332; 18988627; 22135298;
134FTASPASSTTARVITdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated18669648; 16381945; 23193290; 18988627; 22135298; 22817900;
136ASPASSTTARVITNQPhosphoSitePlus;curated22135298; 23090842
141STTARVITNQYNNPAPhosphoPep 2.0;PhosphoSitePlus;curated19060867; 22135298; 25627689
144ARVITNQYNNPAGLYdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;UniProt;curated15592455; 16381945; 23193290; 16497976; 18083107; 18180459;
151YNNPAGLYSSENISNdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;curated15592455; 16381945; 23193290; 16497976; 17360941; 18083107;
152NNPAGLYSSENISNFPhosphoSitePlus22135298
153NPAGLYSSENISNFNPhosphoSitePlus22135298
186LDHAQPPSSLVIDKEdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;curated17287340; 16381945; 23193290; 18988627; 19060867; 22135298;
187DHAQPPSSLVIDKESdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;curated17287340; 16381945; 23193290; 18988627; 19060867; 22135298;
194SLVIDKESEVYKMLQPhosphoSitePlus22135298
197IDKESEVYKMLQEKQdbPTM 3.0;PhosphoSitePlus;curated18180459; 20562096; 20736484; 16381945; 23193290; 22135298;
Sequence
(Fasta)		MTTQQIDLQG PGPWGFRLVG GKDFEQPLAI SRVTPGSKAA LANLCIGDVI TAIDGENTSN 60
MTHLEAQNRI KGCTDNLTLT VARSEHKVWS PLVTEEGKRH PYKMNLASEP QEVLHIGSAH 120
NRSAMPFTAS PASSTTARVI TNQYNNPAGL YSSENISNFN NALESKTAAS GVEANSRPLD 180
HAQPPSSLVI DKESEVYKML QEKQELNEPP KQSTSFLVLQ EILESEEKGD PNKPSGFRSV 240
KAPVTKVAAS IGNAQKLPMC DKCGTGIVGV FVKLRDRHRH PECYVCTDCG TNLKQKGHFF 300
VEDQIYCEKH ARERVTPPEG YEVVTVFPK
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0903--Direct protein sequencing
KW-0440--LIM domain
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0862--Zinc
Interpro

IPR031847--DUF4749
IPR028537--PDLIM1
IPR001478--PDZ
IPR006643--ZASP
IPR001781--Znf_LIM
PROSITE

PS00478--LIM_DOMAIN_1
PS50023--LIM_DOMAIN_2
PS50106--PDZ
Pfam

PF15936--DUF4749
PF00412--LIM
PF00595--PDZ
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005856--C:cytoskeleton
GO:0005925--C:focal adhesion
GO:0005667--C:transcription factor complex
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0001666--P:response to hypoxia
GO:0006979--P:response to oxidative stress